von Willebrand Factor Antibody

von Willebrand Factor Polyclonal Antibody for IF, IHC (P)

>> See 14 other antibodies for VWF (coagulation factor VIII VWF)
Synonyms:
coagulation factor VIII VWF
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu)
Immunogen: Purified factor VIII related antigen/von Willebrand factor
Ordering Information
Pierce von Willebrand Factor Antibody
Product #
PA5-16634
Size
500 ul
Price
$140.00
Purchase
Add von Willebrand Factor Antibody to your cart.
Tested Applications Dilution *
Immunofluorescence (IF) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 1:80-1:160
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Purification: purified
Storage Buffer: PBS, pH 7.4, with 0.2% BSA
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
PA5-16634 targets von Willebrand Factor in IF and IHC (P) applications and shows reactivity with Human samples.

The PA5-16634 immunogen is purified factor VIII related antigen/von Willebrand factor.
General Information
Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein. It has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. von Willebrand factor is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/ store) this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.
Product Images
  • von Willebrand Factor Antibody (PA5-16634) in IHC
    PA5-16634_Immunohistochemistry.jpg

    Immunohistochemistry with anti-von Willebrand Factor Polyclonal Antibody (PA5-16634) (PA5-16634_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-von Willebrand Factor Polyclonal Antibody (PA5-16634)

    Formalin-fixed, paraffin-embedded human tonsil stained with Factor VIII antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of endothelial cells.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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