ChIP Validated Antibodies

Chromatin immunoprecipitation (ChIP) is an effective method for identifying links between the genome and the proteome by monitoring transcription regulation through histone modification (epigenetics) or transcription factor-DNA binding interactions. The strength of the ChIP assay is its ability to capture a snapshot of specific protein-DNA interactions as they occur in living cells, and then quantitate the interactions using quantitative PCR.

To isolate a specific modified histone, transcription factor or co-factor, ChIP-validated antibodies are used to immunoprecipitate and isolate the protein-DNA complexes from other nuclear components. Selection of the appropriate antibody is a critical parameter to successful ChIP assays. ChIP validated antibodies must be high quality and very specific, with the ability to bind the target protein in its chromatin-associated context after cross-linking. Thermo Scientific provides numerous ChIP-grade antibodies that are validated for this procedure.

For more detailed information on ChIP procedure, refer to the ChIP Assay Procedure and Essential Tools, and to ensure even greater ChIP success look for the Pierce Agarose ChIP Kit, both found in the related links below.

For antibodies againgt the protein "CHIP' (Carboxyl Terminus of Hsc70-Interacting Protein), also known as STUB1, click here.

Related Links:
Pierce Magnetic ChIP Kit
Pierce Agarose ChIP Kit
ChIP Assay Procedure and Essential Tools
Overview of Protein-Nucleic Acid Interactions

The following antibodies have been ChIP validated. Use the filter search on the left to find your desired ChIP validated antibody.
Filter Results
By Type
Antibody (395)
Isotype Control (5)
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Polyclonal (241)
Monoclonal (124)
Oligoclonal (30)
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[Hu] Human (390)
[Ms] Mouse (240)
[Rt] Rat (135)
By Host
Rabbit (320)
Mouse (66)
Goat (11)
By Application
ChIP (400)
WB (375)
IF (253)
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H1alpha67 (5)
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Not Labeled (391)
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Biotin (2)
By PTM
Not PTM-specific (307)
PTM-specific (93)
Phosphorylated:pSer10 (5)
Product Description Host Target Species Applications Imgs / Refs Size Product # Price
HNF4A Antibody (H1415) Mouse Hu, Rt WB, IF, IHC, IP, ChIP, ELISA, GS 00 100 µg 417700 $455.00
PPAR gamma Antibody (A3409A) Mouse Hu, Ms, Rt WB, IHC, IP, ChIP, ELISA, GS 00 100 µg 419300 $455.00
Retinoid X Receptor alpha / RXRA Antibody (K8505) Mouse Hu, Ms, Rt WB, IHC, IP, ChIP, ELISA, GS 00 100 µg 433900 $455.00
CIITA Antibody Rabbit Hu ChIP 10 50 µg 49-1001 $319.00
Estrogen Receptor alpha Antibody Mouse Hu WB, IHC, ChIP 30 50 µg 49-1002 $319.00
Histone H3K4me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1003 $339.00
Histone H3K4me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1004 $339.00
Histone H3K4me3 Antibody Rabbit Hu, Ms IF, ChIP, ELISA 40 24 µg 49-1005 $339.00
Histone H3K9me1 Antibody Rabbit Hu WB, IF, ChIP, ELISA 50 100 µL 49-1006 $339.00
Histone H3K9me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1007 $339.00
Histone H3K9me3 Antibody Rabbit Hu, Ms WB, IF, ChIP, ELISA 50 50 µg 49-1008 $339.00
Histone H3K9ac Antibody Rabbit Hu IF, ChIP, ELISA 30 44 µg 49-1009 $339.00
Histone H3K9 / 14ac Antibody Rabbit Hu IF, ChIP, ELISA 10 44 µg 49-1010 $339.00
Phospho-Histone H3K9ac pSer10 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1011 $339.00
Histone H3K27me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1012 $339.00
Histone H3K27me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1013 $339.00
Phospho-Histone H3K27me3 pSer28 Antibody Rabbit Hu WB, IF, ChIP, ELISA 60 100 µL 49-1015 $339.00
Histone H3K36me1 Antibody Rabbit Hu WB, IF, ChIP, ELISA 50 50 µg 49-1016 $379.00
Histone H3K36me3 Antibody Rabbit Hu, Ms WB, ChIP, ELISA 50 50 µg 49-1017 $339.00
Histone H3K79me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1018 $339.00
Histone H3K79me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1019 $339.00
Histone H3K79me3 Antibody Rabbit Hu, Ms WB, ChIP, ELISA 40 50 µg 49-1020 $339.00
Histone H3 R17me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1021 $339.00
Histone H3K8ac Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1022 $339.00
Histone H3K20me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1023 $339.00
Histone H3K20me3 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1024 $339.00
HDAC1 Antibody Rabbit Hu, Ms IF, ChIP, ELISA 40 50 µg 49-1025 $319.00
Glucocorticoid Receptor Antibody Mouse Hu WB, IF, IHC, ChIP, ELISA 60 50 µg 49-1026 $319.00
MBD1 Antibody Rabbit Hu ChIP, ELISA 20 50 µg 49-1027 $319.00
DNMT3B Antibody Rabbit Hu, Ms ChIP, ELISA 20 5 µg 49-1028 $319.00
MECP2 Antibody Rabbit Hu ChIP, ELISA 30 50 µg 49-1029 $319.00
p53 Antibody Rabbit Hu ChIP, ELISA 20 50 µg 49-1031 $319.00
RNA polymerase II Antibody Mouse Hu ChIP 10 100 µL 49-1033 $319.00
RFX-AP Antibody Rabbit Hu ChIP 10 50 µg 49-1034 $320.00
SUZ12 Antibody Rabbit Hu, Ms WB, ChIP 20 50 µg 49-1035 $319.00
TBP Antibody Mouse Hu ChIP 10 100 µg 49-1036 $319.00
TIP5 Antibody Rabbit Hu, Ms WB, ChIP 20 100 µL 49-1037 $319.00
Histone H3 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1038 $339.00
Histone H3K4me3 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1039 $339.00
Phospho-Histone H3K9me3 pSer10 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1040 $379.00
Phospho-Histone H3 pSer10 Antibody Rabbit Hu WB, IF, ChIP, ELISA 00 100 µL 49-1041 $339.00
HDAC3 Antibody Mouse Hu ChIP 00 100 µL 49-1042 $319.00
EZH2 Antibody Rabbit Hu, Ms WB, ChIP 00 50 µg 49-1043 $319.00
Histone H3K27me3 Antibody Rabbit Hu WB, IF, ChIP, ELISA 40 50 µg A15024 $359.00
UHRF1 Antibody Rabbit Hu WB, IF, IHC (P), IP, ChIP 00 100 µl PA5-37440 $394.00
STAT5 beta Antibody (ST5b-10G1) Mouse Hu, Ms, Rt WB, IF, ICC, IP, ChIP, ELISA, GS 70 100 µg 13-5300 $270.00
STAT3 Antibody (ST3-5G7) Mouse Hu, Ms, Rt WB, IP, ChIP, ELISA, GS 10 100 µg 13-7000 $290.00
Phospho-STAT1 pTyr701 Antibody (ST1P-11A5) Mouse Hu, Ms WB, IHC (P), ChIP, ELISA 60 50 µg 33-3400 $260.00
Phospho-CREB pSer129 / pSer133 Antibody Rabbit Hu, Ms WB, IF, ICC, ChIP 50 10 blots 44-297G $299.00
STAT2 Antibody Rabbit Hu WB, IF, ICC, IHC (P), FACS, IP, ChIP 80 100 µL 44-362G $299.00
Phospho-STAT1 pTyr701 Antibody Rabbit Hu, Ms, Rt WB, IF, ICC, IHC (P), FACS, ChIP 70 10 blots 44-376G $299.00
Phospho-STAT1 pSer727 Antibody Rabbit Hu, Ms WB, IF, ICC, IHC (P), FACS, ChIP 60 10 blots 44-382G $299.00
Phospho-STAT3 pSer727 Antibody Rabbit Hu, Ms, Rt WB, IHC (P), ChIP 40 10 blots 44-384G $299.00
Phospho-STAT5 pTyr694 Antibody Rabbit Hu, Ms WB, ChIP 30 10 blots 44-390G $299.00
NFkB p65 Antibody Rabbit Hu, Ms, Nhp WB, IF, ICC, IHC, FACS, ChIP, ELISA 40 100 µg 51-0500 $299.00
HDAC2 Antibody Rabbit Hu, Ms WB, IHC, IP, ChIP, ELISA 00 100 µg 51-5100 $279.00
Phospho-p44 MAPK + p42 MAPK pThr185 + pTyr187 Antibody (15H10L7), ABfinity™Rabbit Monoclonal Rabbit Hu, Rt WB, IF, ICC, IHC (P), FACS, ChIP, ELISA 71 100 µg 700012 $299.00
IRAK-1 Antibody (19H32L12), ABfinity™Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 700025 $299.00
IRAK-4 Antibody (12H2L6), ABfinity™Rabbit Monoclonal Rabbit Hu IF, ICC, FACS, ChIP 40 100 µg 700026 $299.00
Phospho-JAK1 pTyr1022+1023 Antibody (59H4L5), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms WB, IF, ICC, ChIP 30 100 µg 700028 $299.00
Phospho-JNK1 + JNK2 pThr183 + pTyr185 Antibody (D12H7L17), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms WB, IF, ICC, IHC (P), FACS, ChIP, ELISA 90 100 µg 700031 $299.00
SMAD2 Antibody (31H15L4), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP, ELISA 70 100 µg 700048 $299.00
Phospho-SMAD2 pThr8 Antibody (11H10L30), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP 60 100 µg 700050 $299.00
FAK2 / PYK2 Antibody (9H12L1), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, IHC (P), FACS, ChIP 60 100 µg 700183 $299.00
IRF-2 Antibody (B-80 H53L46), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms, Rt WB, IF, ICC, ChIP 30 100 µg 700226 $299.00
Phospho-STAT6 pTyr641 Antibody (46H1L12), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms WB, IF, ICC, IHC (P), FACS, ChIP, ELISA 110 100 µg 700247 $299.00
Phospho-p53 pSer15 Antibody (14H61L24), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP, FRET 60 100 µg 700439 $299.00
HIF-1 alpha Antibody (16H4L13), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP, ELISA 50 100 µg 700505 $299.00
Phospho-FAK2 / PYK2 pTyr402 Antibody (17H4L19), ABfinity™Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 700632 $299.00
MAP1LC3B Antibody (2H30L32), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms, Rt WB, IF, ICC, IHC (P), FACS, IP, ChIP 92 100 µg 700712 $299.00
Phospho-STAT5 alpha pTyr694 Antibody (6H5L15), ABfinity™Rabbit Monoclonal Rabbit Hu, Ms WB, IF, ICC, IHC (P), FACS, ChIP 80 100 µg 701063 $299.00
Phospho-GSK3 beta pSer9 Antibody (5H1L11), ABfinity™Rabbit Monoclonal Rabbit Hu WB, ChIP 50 100 µg 701069 $299.00
Phospho-p70 S6 Kinase pThr421+pSer424 Antibody (B12H16L8), ABfinity™Rabbit Monoclonal Rabbit Hu, Rt WB, FACS, ChIP 50 100 µg 701083 $299.00
STAT5 alpha Antibody (6H2L9), ABfinity™Rabbit Monoclonal Rabbit Hu WB, FACS, ChIP 30 100 µg 701108 $299.00
STAT5 beta Antibody (13H20L4), ABfinity™Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP 50 100 µg 701109 $299.00