ChIP Validated Antibodies

Chromatin immunoprecipitation (ChIP) is an effective method for identifying links between the genome and the proteome by monitoring transcription regulation through histone modification (epigenetics) or transcription factor-DNA binding interactions. The strength of the ChIP assay is its ability to capture a snapshot of specific protein-DNA interactions as they occur in living cells, and then quantitate the interactions using quantitative PCR.

To isolate a specific modified histone, transcription factor or co-factor, ChIP-validated antibodies are used to immunoprecipitate and isolate the protein-DNA complexes from other nuclear components. Selection of the appropriate antibody is a critical parameter to successful ChIP assays. ChIP validated antibodies must be high quality and very specific, with the ability to bind the target protein in its chromatin-associated context after cross-linking. Thermo Scientific provides numerous ChIP-grade antibodies that are validated for this procedure.

For more detailed information on ChIP procedure, refer to the ChIP Assay Procedure and Essential Tools, and to ensure even greater ChIP success look for the Pierce Agarose ChIP Kit, both found in the related links below.

For antibodies againgt the protein "CHIP' (Carboxyl Terminus of Hsc70-Interacting Protein), also known as STUB1, click here.

Related Links:
Pierce Magnetic ChIP Kit
Pierce Agarose ChIP Kit
ChIP Assay Procedure and Essential Tools
Overview of Protein-Nucleic Acid Interactions

The following antibodies have been ChIP validated. Use the filter search on the left to find your desired ChIP validated antibody.
Filter Results
By Type
Antibody (395)
Isotype Control (5)
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Polyclonal (250)
Monoclonal (129)
Oligoclonal (16)
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[Hu] Human (389)
[Ms] Mouse (245)
[Rt] Rat (145)
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Rabbit (310)
Mouse (75)
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By Application
ChIP (400)
WB (373)
IF (235)
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H1alpha67 (5)
9HCLC (3)
TE111.5D11 (3)
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Not Labeled (391)
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Not PTM-specific (305)
PTM-specific (95)
Phosphorylated:pSer10 (4)
Product Description Host Target Species Applications Imgs / Refs Size Product # Price
HNF4A Antibody (H1415) Mouse Hu, Rt WB, IF, IHC, IP, ChIP, ELISA, GS 00 100 µg 417700
PPAR gamma Antibody (A3409A) Mouse Hu, Ms, Rt WB, IHC, IP, ChIP, ELISA, GS 00 100 µg 419300
Retinoid X Receptor alpha / RXRA Antibody (K8505) Mouse Hu, Ms, Rt WB, IHC, IP, ChIP, ELISA, GS 00 100 µg 433900
CIITA Antibody Rabbit Hu ChIP 10 50 µg 49-1001
Estrogen Receptor alpha Antibody Mouse Hu WB, IHC, ChIP 30 50 µg 49-1002
Histone H3K4me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1003
Histone H3K4me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1004
Histone H3K4me3 Antibody Rabbit Hu, Ms IF, ChIP, ELISA 40 24 µg 49-1005
Histone H3K9me1 Antibody Rabbit Hu WB, IF, ChIP, ELISA 50 100 µL 49-1006
Histone H3K9me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1007
Histone H3K9me3 Antibody Rabbit Hu, Ms WB, IF, ChIP, ELISA 50 50 µg 49-1008
Histone H3K9ac Antibody Rabbit Hu IF, ChIP, ELISA 30 44 µg 49-1009
Histone H3K9 / 14ac Antibody Rabbit Hu IF, ChIP, ELISA 10 44 µg 49-1010
Phospho-Histone H3K9ac pSer10 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1011
Histone H3K27me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1012
Histone H3K27me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 50 µg 49-1013
Phospho-Histone H3K27me3 pSer28 Antibody Rabbit Hu WB, IF, ChIP, ELISA 60 100 µL 49-1015
Histone H3K36me1 Antibody Rabbit Hu WB, IF, ChIP, ELISA 50 50 µg 49-1016
Histone H3K36me3 Antibody Rabbit Hu, Ms WB, ChIP, ELISA 50 50 µg 49-1017
Histone H3K79me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1018
Histone H3K79me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1019
Histone H3K79me3 Antibody Rabbit Hu, Ms WB, ChIP, ELISA 40 50 µg 49-1020
Histone H3 R17me2 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1021
Histone H3K8ac Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1022
Histone H3K20me1 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1023
Histone H3K20me3 Antibody Rabbit Hu WB, ChIP, ELISA 40 100 µL 49-1024
HDAC1 Antibody Rabbit Hu, Ms IF, ChIP, ELISA 40 50 µg 49-1025
Glucocorticoid Receptor Antibody Mouse Hu WB, IF, IHC, ChIP, ELISA 60 50 µg 49-1026
MBD1 Antibody Rabbit Hu ChIP, ELISA 20 50 µg 49-1027
DNMT3B Antibody Rabbit Hu, Ms ChIP, ELISA 20 5 µg 49-1028
MECP2 Antibody Rabbit Hu ChIP, ELISA 30 50 µg 49-1029
NF-YB Antibody Rabbit Hu IF, ChIP 30 100 µg 49-1030
p53 Antibody Rabbit Hu ChIP, ELISA 20 50 µg 49-1031
RNA polymerase II Antibody Mouse Hu ChIP 10 100 µL 49-1033
RFX-AP Antibody Rabbit Hu ChIP 10 50 µg 49-1034
SUZ12 Antibody Rabbit Hu, Ms WB, ChIP 20 50 µg 49-1035
TBP Antibody Mouse Hu ChIP 10 100 µg 49-1036
TIP5 Antibody Rabbit Hu, Ms WB, ChIP 20 100 µL 49-1037
Histone H3 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1038
Histone H3K4me3 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1039
Phospho-Histone H3K9me3 pSer10 Antibody Rabbit Hu WB, ChIP, ELISA 00 100 µL 49-1040
Phospho-Histone H3 pSer10 Antibody Rabbit Hu WB, IF, ChIP, ELISA 00 100 µL 49-1041
HDAC3 Antibody Mouse Hu ChIP 00 100 µL 49-1042
EZH2 Antibody Rabbit Hu, Ms WB, ChIP 00 50 µg 49-1043
Histone H3K27me3 Antibody Rabbit Hu WB, IF, ChIP, ELISA 40 50 µg A15024
UHRF1 Antibody Rabbit Hu WB, IF, IHC (P), IP, ChIP 00 100 µl PA5-37440
STAT5 beta Antibody (ST5b-10G1) Mouse Hu, Ms, Rt WB, IF, ICC, IP, ChIP, ELISA, GS 40 100 µg 13-5300
STAT3 Antibody (ST3-5G7) Mouse Hu, Ms, Rt WB, IP, ChIP, ELISA, GS 10 100 µg 13-7000
HDAC2 Antibody Rabbit Hu, Ms WB, IHC, IP, ChIP, ELISA 00 100 µg 51-5100
Phospho-p44 MAPK + p42 MAPK pThr185 + pTyr187 Antibody (15H10L7), Abfinity™ Rabbit Monoclonal Rabbit Hu, Rt WB, IHC (P), ChIP, ELISA 41 100 µg 700012
IRAK-1 Antibody (19H32L12), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 700025
IRAK-4 Antibody (12H2L6), Abfinity™ Rabbit Monoclonal Rabbit Hu IF, ICC, FACS, ChIP 40 100 µg 700026
Phospho-JAK1 pTyr1022+1023 Antibody (59H4L5), Abfinity™ Rabbit Monoclonal Rabbit Hu, Ms WB, ChIP 20 100 µg 700028
Phospho-JNK1 + JNK2 pThr183 + pTyr185 Antibody (D12H7L17), Abfinity™ Rabbit Monoclonal Rabbit Hu, Ms WB, IF, ICC, IHC (P), FACS, ChIP, ELISA 90 100 µg 700031
Phospho-SMAD2 pThr8 Antibody (11H10L30), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 700050
FAK2 / PYK2 Antibody (9H12L1), Abfinity™ Rabbit Monoclonal Rabbit Hu IF, ICC, IHC (P), FACS, ChIP 40 100 µg 700183
IRF-2 Antibody (B-80 H53L46), Abfinity™ Rabbit Monoclonal Rabbit Hu, Ms, Rt WB, IF, ICC, ChIP 30 100 µg 700226
Phospho-STAT6 pTyr641 Antibody (46H1L12), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, ChIP, ELISA 40 100 µg 700247
Phospho-p53 pSer15 Antibody (14H61L24), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP, FRET 60 100 µg 700439
HIF-1 alpha Antibody (16H4L13), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP, ELISA 50 100 µg 700505
Phospho-FAK2 / PYK2 pTyr402 Antibody (17H4L19), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 700632
MAP1LC3B Antibody (2H30L32), Abfinity™ Rabbit Monoclonal Rabbit Hu, Ms, Rt WB, IF, ICC, IHC (P), FACS, IP, ChIP 92 100 µg 700712
Phospho-STAT5 alpha pTyr694 Antibody (6H5L15), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 701063
Phospho-GSK3 beta pSer9 Antibody (5H1L11), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 701069
Phospho-p70 S6 Kinase pThr421+pSer424 Antibody (B12H16L8), Abfinity™ Rabbit Monoclonal Rabbit Hu, Rt WB, FACS, ChIP 50 100 µg 701083
CREB Antibody (3H8L15), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP 60 100 µg 701120
PDGF-RA / CD140a Antibody (7H13L1), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, ChIP 30 100 µg 701142
SMAD1 Antibody (12H1L14), Abfinity™ Rabbit Monoclonal Rabbit Hu, Ms WB, ChIP 20 100 µg 701168
Ki-67 Antibody (12H15 L5), Abfinity™ Rabbit Monoclonal Rabbit Hu IF, ICC, FACS, ChIP 30 100 µg 701198
Phospho-MEK1 / MAP2K1 pSer217+221 Antibody (13H22L22), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, ChIP 20 100 µg 701267
Acetyl-Histone H3 (Lys9) Antibody (17H12L11), Abfinity™ Rabbit Monoclonal Rabbit Hu, Rt WB, IF, ICC, ChIP 30 100 µg 701269
Ubiquitin Antibody (10H4L21), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, ChIP 30 100 µg 701339
S6 Ribosomal Protein Antibody (9H8L2), Abfinity™ Rabbit Monoclonal Rabbit Hu WB, IF, ICC, FACS, ChIP 40 100 µg 701374
STAT4 Antibody Rabbit Hu, Ms, Rt WB, IP, ChIP, ELISA, GS 10 100 µg 71-4500
Phospho-p38 MAPK / MAPK14 pThr180+pTyr182 Antibody (B10HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, ChIP 20 100 µg 710088
Phospho-STAT5 alpha pTyr694 Antibody (6HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, ChIP 20 100 µg 710094
Phospho-p70 S6 Kinase pThr389 Antibody (B2HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu, Rt WB, IF, ICC, FACS, ChIP 50 100 µg 710095
Phospho-GSK3 beta pSer9 Antibody (9HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, IF, ICC, ChIP 40 100 µg 710100
PDGF-RA / CD140a Antibody (7HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, IF, ICC, ChIP 30 100 µg 710169
PAX3 Antibody (16HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, IF, ICC, ChIP 30 100 µg 710178
Rex1 Antibody (14HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu, Rt WB, IF, ICC, ChIP 30 100 µg 710190
ERK2 / MAPK1 + ERK1 / MAPK3 Antibody (3HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu, Rt WB, ChIP 30 100 µg 710214
Ki-67 Antibody (12HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu IF, ICC, ChIP 30 100 µg 710229
ICAM-1 / CD54 Antibody (9HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, IF, ICC, ChIP 40 100 µg 710278
Phospho-Histone H3 pSer10 Antibody (9HCLC), Abfinity™ Rabbit Oligoclonal Rabbit Hu WB, IF, ICC, ChIP 30 100 µg 710282