This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
eEF2k Antibody (PA5-17720) in IF eEF2k-PA5-17720-Antibody-Immunofluorescence-IF-2A.jpg
Immunofluorescence with anti-eEF2k Polyclonal Antibody (PA5-17720)
Immunofluorescent analysis of eEF2k in HeLa cells using an EEF2k polyclonal antibody (Product # PA5-17720) (green). Actin filaments are labeled with a fluorescent red phalloidin. DNA is labeled using a fluorescent blue dye.
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