PA5-17720 targets eEF2k in ICC, IP, and WB applications and shows reactivity with Human, Non-human primate, and Rat samples.
The PA5-17720 immunogen is synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2k.
PA5-17720 detects eEF2k which has a predicted molecular weight of approximately 105 kDa.
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
eEF2k Antibody (PA5-17720) in IF eEF2k_PA5-17720_Antibody_Immunofluorescence(IF)_2A.jpg
Immunofluorescence with anti-eEF2k Polyclonal Antibody (PA5-17720)
Immunofluorescent analysis of eEF2k in HeLa cells using an EEF2k polyclonal antibody (Product # PA5-17720) (green). Actin filaments are labeled with a fluorescent red phalloidin. DNA is labeled using a fluorescent blue dye.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)