Part of Thermo Fisher Scientific

beta-2 Arrestin Polyclonal Antibody

beta-2 Arrestin Antibody for ELISA, Western blot

Synonyms:
beta-arrestin2, SAG, S-Arrestin
Entrez Gene ID:
(Human) 216869
UniProt ID:
Q91YI4
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: Synthetic peptide (amino acids 195-350) of human Arrestin beta-2.
Ordering Information
Pierce beta-2 Arrestin Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-30077 100 µg $382.00
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This product is not available outside of the U.S.

Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: 100 µg of affinity purified antibody in PBS buffer .Lyophilized. Redissolving the powder with 100µL of sterile water will restore to the original concentration to 1mg/mL.


Applications Dilution *
Western Blot (WB) 1:1,000
ELISA (ELISA) 1:5,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-30077 detects beta 2 Arrestin in human, mouse and rat samples.

GB-30077 has been successfully used in ELISA and Western blot procedures.

The GB-30077 immunogen is a synthetic peptide located on the putative C-terminal domain corresponding to residues 195-350) of human Arrestin beta-2. The peptide immunogen is conserved with the rat and mouse counterparts.

For short term storage, store at 4ºC. For long term storage, store at -20ºC.
General Information
Members of arrestin / beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neuro transmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from the thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)