WFS1 Antibody

WFS1 Polyclonal Antibody for Western blot, IF, ICC, IHC (F), IHC (P), IP

Synonyms:
Wolfram antibody, wolfram syndrome 1 antibody.
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Non-human primate (Nhp)
Immunogen: A 110 amino acid region of the N-terminal region of the human WFS1 protein.
Ordering Information
Pierce WFS1 Antibody
Product #
PA1-16923
Size
100 µl
Price
$299.00
Purchase
Add WFS1 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:500-1:2000
Immunofluorescence (IF) 1:200
Immunocytochemistry (ICC) 1:200
Immunohistochemistry (Frozen) (IHC (F)) 1:1000
Immunohistochemistry (Paraffin) (IHC (P)) 1:1000
Immunoprecipitation (IP) 2 µl
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Storage Buffer: whole serum
Preservative: no preservative
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
In Western blot, bands are observed at ~100 kDa and ~200 kDa representing the monomer and dimer forms of WFS1.

Suggested positive control: antigen standard for WFS1 (transient overexpression lysate).
General Information
WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. WFS1 plays an important role in maintaining homeostasis of the endoplasmic reticulum (ER) in the pancreas. It is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major involvement in Wolfram syndrome.
Product Images
  • WFS1 Antibody (PA1-16923) in WB
    PA1-16923_Westernblot.jpg

    Western Blot with anti-WFS1 Polyclonal Antibody (PA1-16923) (PA1-16923_Westernblot.jpg)

    Western Blot with anti-WFS1 Polyclonal Antibody (PA1-16923)

    Western Blot detection of WFS1 in insulinoma cells in WB using PA1-16923.
  • WFS1 Antibody (PA1-16923) in IP
    PA1-16923_Immunoprecipitation.jpg

    Immunoprecipitation with anti-WFS1 Polyclonal Antibody (PA1-16923) (PA1-16923_Immunoprecipitation.jpg)

    Immunoprecipitation with anti-WFS1 Polyclonal Antibody (PA1-16923)

    Immunoprecipitation of WFS1 using PA1-16923. Precipitated lysate is INS-1.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific