Part of Thermo Fisher Scientific

VEGF Receptor 3 Polyclonal Antibody

VEGF Receptor 3 Antibody for ELISA

Synonyms:
FLT41, PCL, FLT4
Entrez Gene ID:
(Human) 2324, (Murine) 14257, (Rat) 114110
UniProt ID:
P35916
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: synthetic peptide of human VEGFR-3.
Ordering Information
Pierce VEGF Receptor 3 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-30015 250 µl $344.00
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This product is not available outside of the U.S.

Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 250 µl of antibody provided as antiserum in lyophilized powder. Redissolve the powder with 250 microliters sterile water to restore to the original concentration.


Applications Dilution *
ELISA (ELISA) 1:5,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-30015 detects VEGFR3 in human, mouse and rat samples.

GB-30015 has been successfully used in ELISA procedures.

The GB-30015 immunogen is a synthetic peptide of human VEGFR-3 located within the putative 4th Immunoglobulin like (IG like) domain corresponding to residues 430-552.
General Information
Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)