* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
PBS, pH 7.4,
0.09% sodium azide
Product Specific Information
MA5-11783 targets Tropomyosin in IF and IHC (P) applications and shows reactivity with Chicken, Human, and Rat samples.
The MA5-11783 immunogen is tropomyosin protein purified from chicken embryo fibroblasts (CEF) and chicken leg, heart, and gizzard.
Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.
Tropomyosin Antibody (MA5-11783) in IHC MA5-11783_Immunohistochemistry.jpg
Immunohistochemistry with anti-Tropomyosin Monoclonal Antibody [CH1] (MA5-11783)