Part of Thermo Fisher Scientific

Thyroid Stimulating Hormone Rec. Polyclonal Antibody

Thyroid Stimulating Hormone Rec. Antibody for ELISA

Synonyms:
TSH Receptor
Entrez Gene ID:
(Human) 7253
UniProt ID:
P16473
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide of human thyroid stimulating hormone receptor.
Ordering Information
Pierce Thyroid Stimulating Hormone Rec. Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-30094 100 µg $293.00
Add Thyroid Stimulating Hormone Rec. Polyclonal Antibody to your cart.

This product is not available outside of the U.S.

Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 μg of affinity purified antibody.


Applications Dilution *
ELISA (ELISA) 1:10,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-30094 detects Thyroid Stimulating Hormone Receptor in human samples.

GB-30094 has been successfully used in ELISA procedures.

The GB-30094 immunogen is a synthetic peptide located on the putative extracellular domain of human thyroid stimulating hormone receptor.
General Information
The thyroid stimulating hormone (thyrotropin) receptor (TSHR) is expressed on the surface of thyrocyte cell membranes and is crucial for thyroid gland growth and function. TSHR’s are targets for the pathogenesis of many autoimmune diseases including Graves’ disease and primary myxedema. This 7-transmembrane-domain protein contains 5 potential extracellular N-linked glycosylation sites. Antibodies to TSHR can affect receptor function in a number of different ways. TSHR antibodies which can inhibit TSH binding to the receptor are called TSH binding inhibitor immunoglobulins or TBIIs.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)