Synthetic peptide from the C-terminal region of TRKA conjugated to KLH.
Pierce TRKA Antibody
Western Blot (WB)
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form information is not available for this product.
Product Specific Information
PA5-14744 targets TRKA in WB and IHC applications and shows reactivity with Human and Mouse samples. The PA5-14744 immunogen is a synthetic peptide from the C-terminal region of TRKA conjugated to KLH. PA5-14744 detects TRKA which has a predicted molecular weight of approximately 88 kDa.
This gene encodes a member of the neurotrophic tyrosine kinase receptor family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
TRKA Antibody (PA5-14744) in WB TRKA_Antibody_PA5-14744_WesternBlot(WB).jpg
Western Blot with anti-TRKA Polyclonal Antibody (PA5-14744)