TNF Alpha Antibody

TNF Alpha Polyclonal Antibody for Western blot, ELISA

>> See 44 other antibodies for TNF (TNF-a; TNF-alpha; cachectin; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor, alpha (TNF superfamily, member 2))
Synonyms:
TNF-a; TNF-alpha; cachectin; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor, alpha (TNF superfamily, member 2)
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Bovine (Bv)
Published Species Reactivity: Bovine (Bv)
Immunogen: TNF alpha
Ordering Information
Pierce TNF Alpha Antibody
Product #
PBOTNFAI
Size
1 mg
Price
$316.00
Purchase
Add TNF Alpha Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) Assay Dependent
ELISA (ELISA) Assay Dependent
Published Applications Dilution
Western Blot (WB) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Lyophilized
Purification: Protein G
Storage Buffer: PBS
Preservative: no preservative
Storage Conditions: 4° C
Product Specific Information
PBOTNFAI targets TNF Alpha in ELISA, and WB applications and shows reactivity with Bovine samples.

The PBOTNFAI immunogen is tNF alpha.

PBOTNFAI detects TNF Alpha which has a predicted molecular weight of approximately 26 kDa.
General Information
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Publications:
Western Blot
  Species / Dilution Summary
  Bv / Not Cited
PBOTNFAI was used in western blot to investigate the involvement of the NF-kB pathway and TNF-alpha in the cytotoxicity of anthrax lethal toxin

Vet Microbiol. 2010 Nov 20;146(1-2):111-7.
"Activation of NF-?B pathway and TNF-? are involved in the cytotoxicity of anthrax lethal toxin in bovine BoMac macrophages."
Author(s): Liang X, Gao CF, Rutherford MS, Ji Y
Number of Citations: 0
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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