* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
0.5% proprietary stabilizer
0.05% sodium azide
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
MA5-17181 targets SRY in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
SRY Antibody (MA5-17181) in WB SRY_Antibody_MA5-17181_Westernblot1-1252013.jpg
Western Blot with anti-SRY Monoclonal Antibody [1G4] (MA5-17181)