| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Mouse (Ms) Rat (Rt) |
| Immunogen: | synthetic peptide GDGHHHGDHTGQTHG conjugated to BSA, corresponding to amino acids 209-223 of Human SOX8. |
| Ordering Information | ||||
| Pierce SOX8 Antibody |
| Storage: | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Form: | 50 ug of immunoaffinity purified antibody (1 mg/ml) in PBS, pH 7.2, with 50% glycerol and 0.09% sodium azide. |
| Applications | Dilution * |
| Immunoprecipitation (IP) | Assay dependent |
| Immunohistochemistry (IHC) | 1:200 - 1:1000 |
| Western Blot (WB) | 1:200 - 1:1000 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA1-28072 detects SOX8 from rat, human, and mouse samples. PA1-28072 has been successfully used in immunohistochemistry, immunoprecipitation, and Western blot applications. The PA1-28072 immunogen is synthetic peptide: GDGHHHGDHTGQTHG conjugated to BSA, corresponding to amino acids 209-223 of Human SOX8. Store at 4ºC short term. For extended storage aliquot and store at -20ºC, avoiding freeze/thaw cycles. |
| General Information |
| This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). |