* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
0.5% proprietary stabilizer
0.05% sodium azide
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
MA5-17171 targets SERPINE1 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17171 immunogen is purified recombinant fragment of human SERPINE1 expressed in E. Coli.
MA5-17171 detects SERPINE1 which has a predicted molecular weight of approximately 45kDa.
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
SERPINE1 Antibody (MA5-17171) in WB SERPINE1_Antibody_MA5-17171_Westernblot1-1252013.jpg
Western Blot with anti-SERPINE1 Monoclonal Antibody [1D5] (MA5-17171)