Pyruvate Dehydrogenase Antibody

Pyruvate Dehydrogenase Polyclonal Antibody for Western blot

>> See 5 other antibodies for PDHA1 (PDHE1-A type I; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase complex, E1-alpha polypeptide 1)
Synonyms:
PDHE1-A type I; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase complex, E1-alpha polypeptide 1
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Non-human primate (Nhp)
Immunogen: Synthetic peptide corresponding to the sequences of both a1 and a2 subunits of human pyruvate dehydrogenase
Ordering Information
Pierce Pyruvate Dehydrogenase Antibody
Product #
PA5-17190
Size
100 ul
Price
$250.00
Purchase
Add Pyruvate Dehydrogenase Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Purification: Antigen affinity chromatography
Storage Buffer: 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol
Preservative: no preservative
Storage Conditions: -20°C
Product Specific Information
It is not recommended to aliquot this antibody.
General Information
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Images
  • Pyruvate Dehydrogenase Antibody (PA5-17190) in WB
    PA5-17190_WesternBlot.jpg

    Western Blot with anti-Pyruvate Dehydrogenase Polyclonal Antibody (PA5-17190) (PA5-17190_WesternBlot.jpg)

    Western Blot with anti-Pyruvate Dehydrogenase Polyclonal Antibody (PA5-17190)

    Western blot analysis of Pyruvate Dehydrogenase in extracts from HepG2 and 293 cells using Pyruvate Dehydrogenase polyclonal antibody (Product # PA5-17190).
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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