Protein C Antibody

Protein C Polyclonal Antibody for Western blot, IF, ICC, IHC (P)

>> See 17 other antibodies for PROC (APC, PC, PROC1, anticoagulant protein C, autoprothrombin IIA, blood coagulation factor XIV, vitamin K-dependent protein C)
Synonyms:
APC, PC, PROC1, anticoagulant protein C, autoprothrombin IIA, blood coagulation factor XIV, vitamin K-dependent protein C
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu)
Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 236 of Human Protein C
Ordering Information
Pierce Protein C Antibody
Product #
PA5-28321
Size
100 µL
Price
$324.00
Purchase
Tested Applications Dilution *
Western Blot (WB) 1:500-1:3000
Immunofluorescence (IF) 1:100-1:1000
Immunocytochemistry (ICC) 1:100-1:1000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS, pH 7, with 1% BSA, 20% glycerol
Preservative: 0.01% thimerosal
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-28321 targets Protein C in IF, IHC (P), and WB applications and shows reactivity with Human samples.

The PA5-28321 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 236 of Human Protein C.
General Information
The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.
Product Images
  • Protein C Antibody (PA5-28321) in WB
    PA5-28321_WB.jpg

    Western Blot with anti-Protein C Polyclonal Antibody (PA5-28321) (PA5-28321_WB.jpg)

    Western Blot with anti-Protein C Polyclonal Antibody (PA5-28321)

    Western blot analysis of Protein C using 30µg of A) HepG2 and B) HCT116 lysate. Samples were loaded onto a 10% SDS-PAGE gel and probed with a Protein C polyclonal antibody (Product # PA5-28321) at a dilution of 1:1000.
  • Protein C Antibody (PA5-28321) in IF
    PA5-28321_IF.jpg

    Immunofluorescence with anti-Protein C Polyclonal Antibody (PA5-28321) (PA5-28321_IF.jpg)

    Immunofluorescence with anti-Protein C Polyclonal Antibody (PA5-28321)

    Immunofluorescent analysis of Protein C in methanol-fixed HeLa cells using a Protein C polyclonal antibody (Product # PA5-28321) at a 1:500 dilution.
  • Protein C Antibody (PA5-28321) in IHC (P)
    PA5-28321_IHC.jpg

    Immunohistochemistry (Paraffin) with anti-Protein C Polyclonal Antibody (PA5-28321) (PA5-28321_IHC.jpg)

    Immunohistochemistry (Paraffin) with anti-Protein C Polyclonal Antibody (PA5-28321)

    Immunohistochemical analysis of Protein C in paraffin-embedded breast carcinoma using a Protein C polyclonal antibody (Product # PA5-28321) at a dilution of 1:250.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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