Plasminogen Antibody (SBF1)

Plasminogen Monoclonal Antibody for Western blot

>> See 22 other antibodies for PLG (plasmin)
Synonyms:
plasmin
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: SBF1
Tested Species Reactivity: Human (Hu)
Published Species Reactivity: Human (Hu), Rat (Rt)
Immunogen: Human plasminogen protein
Ordering Information
Pierce Plasminogen Antibody (SBF1)
Product #
MA5-13849
Size
500 ul
Price
$316.00
Purchase
Add Plasminogen Antibody (SBF1) to your cart.
Tested Applications Dilution *
Western Blot (WB) 1-2 µg/ml
Published Applications Dilution
Western Blot (WB) See publications below
Immunohistochemistry (IHC) See publications below
ELISA (ELISA) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.2mg/ml
Purification: Protein G
Storage Buffer: PBS, pH 7.4, with 0.2% BSA
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
MA5-13849 targets Plasminogen in WB applications and shows reactivity with Human samples.

The MA5-13849 immunogen is human plasminogen protein.
General Information
Plasminogen is a key proenzyme of plasmin in the fibrinolytic and thrombolytic systems, the deficiency of which leads to a mild thrombotic tendency. Plasminogen binds to fibrin as well as to the surface of endothelial cells and monocytes/macrophages, where it is activated to plasmin. Streptokinase is a plasminogen activator widely used in treating blood-clotting disorders. Complexes of streptokinase with human plasminogen can hydrolytically activate other plasminogen molecules to plasmin, which then dissolves blood clots. Apolipoprotein(a) is very similar to plasminogen in terms of amino acid sequence, it inhibits plasmin generation by competing with plasminogen's binding to fibrin and endothelial cells.
Product Images
  • Plasminogen Antibody (MA5-13849) in WB
    MA5-13849_WesternBlot.jpg

    Western Blot with anti-Plasminogen Monoclonal Antibody [SBF1] (MA5-13849) (MA5-13849_WesternBlot.jpg)

    Western Blot with anti-Plasminogen Monoclonal Antibody [SBF1] (MA5-13849)

    Western blot of Plasminogen using Plasminogen Monoclonal Antibody (MA5-13849) on HUVEC Cells.
Publications:
Western Blot
  Species / Dilution Summary
  Hu / 1:200
MA5-13849 was used in immunohistochemistry and western blot to study the source and role of septic-thrombi-associated protease activity in infective endocarditis valve destruction

PLoS One. 2012;7(9):e45695.
"Role of vegetation-associated protease activity in valve destruction in human infective endocarditis."
Author(s): Al-Salih G, Al-Attar N, Delbosc S, Louedec L, Corvazier E, Loyau S, Michel JB, Pidard D, Duval X, Meilhac O
Number of Citations: 1
(See PubMed article )
Immunohistochemistry
  Species / Dilution Summary
  Hu / 1:20
MA5-13849 was used in immunohistochemistry and western blot to study the source and role of septic-thrombi-associated protease activity in infective endocarditis valve destruction

PLoS One. 2012;7(9):e45695.
"Role of vegetation-associated protease activity in valve destruction in human infective endocarditis."
Author(s): Al-Salih G, Al-Attar N, Delbosc S, Louedec L, Corvazier E, Loyau S, Michel JB, Pidard D, Duval X, Meilhac O
Number of Citations: 1
(See PubMed article )
ELISA
  Species / Dilution Summary
  Rt / 1:150
MA5-13849 was used in ELISA to study the mechanism of HGF-regulated TGF-beta1 activation in hepatocytes and stellate cells and the significance for hepatic fibrosis

J Cell Physiol. 2013 Feb;228(2):393-401.
"HGF regulates the activation of TGF-?1 in rat hepatocytes and hepatic stellate cells."
Author(s): Narmada BC, Chia SM, Tucker-Kellogg L, Yu H
Number of Citations: 3
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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