Part of Thermo Fisher Scientific

Peptide histidine-methionine Monoclonal Antibody

Peptide histidine-methionine Antibody for ELISA

Synonyms:
MGC13587, PHM27
Entrez Gene ID:
(Human) 7432
UniProt ID:
P01282
Details
Host / Isotype: Mouse / IgG2a, kappa
Class: Monoclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic human peptide histidine-methionine.
Ordering Information
Pierce Peptide histidine-methionine Monoclonal Antibody
Product Number Pkg. Size Price Purchase
ABS 020-03-02 200 µl $362.00
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Storage: 4º C
Form: 200 ul of antibody in 0.01 M phosphate buffer with 0.5 M NaCl and 15 mM sodium azide; pH 7.4.


Applications Dilution *
ELISA (ELISA) 1:2,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
ABS 020-03-02 detects PHM in human samples.

ABS 020-03-02 has been successfully used in ELISA procedures. PHM cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition).

The ABS 020-03-02 immunogen is s synthetic human peptide histidine-methionine (PHM) coupled to a carrier.
General Information
Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)