MA5-14952 targets PP2A A Subunit in ICC, IHC (P), and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples.
The MA5-14952 immunogen is synthetic peptide corresponding to the sequence of human PP2A A Subunit protein.
MA5-14952 detects PP2A A Subunit which has a predicted molecular weight of approximately 62 kDa.
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
PP2A A Subunit Antibody (MA5-14952) in IF MA5-14952_Immunofluorescence(IF)_1.jpg
Immunofluorescence with anti-PP2A A Subunit Monoclonal Antibody [J.613.4] (MA5-14952)