PNR Antibody

PNR Polyclonal Antibody for Western blot

>> See 4 other antibodies for NR2E3 (Photoreceptor-Specific Nuclear Receptor, NR2E3)
Synonyms:
Photoreceptor-Specific Nuclear Receptor, NR2E3
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Rat (Rt)
Immunogen: Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR.
Ordering Information
Pierce PNR Antibody
Product #
PA1-809
Size
100 µg
Price
$316.00
Purchase
Add PNR Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 2 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS with 1mg/ml BSA
Preservative: 0.05% sodium azide
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA1-809 detects PNR from rat and human samples.

PA1-809 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~42 kDa protein representing PNR from rat tissue extracts.

The PA1-809 immunogen is a synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR. This sequence is completely conserved between mouse and chicken. This immunizing peptide (cat. # PEP-237) can be used for neutralization and control experiments.

General Information
The photoreceptor-specific nuclear receptor (PNR) is a recently identified nuclear transcription factor.  PNR expression pattern appears to be restricted in the retina, specific to photoreceptor cells.  PNR has been shown to share structural similarity with TLX, an orphan receptor. 

Despite distinct differences in the DNA binding domain, studies have shown that PNR is capable of recognizing a subset of TLX target sequences in vitro.  Recent studies suggest that PNR plays a support role in the regulation of signaling pathways intrinsic to the photoreceptor cell function.

The corresponding gene for the PNR is NR2E3.
Product Images
  • PNR Antibody (PA1-809) in WB
    PA1-809_1_07232010.jpg

    Western Blot with anti-PNR Polyclonal Antibody (PA1-809) (PA1-809_1_07232010.jpg)

    Western Blot with anti-PNR Polyclonal Antibody (PA1-809)

    Western blot of PNR in whole rat eye extracts using PA1-809.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific