* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
0.05% sodium azide
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
MA1-46002 detects PMP22 protein in human and non-human primate samples.
MA1-46002 has been successfully used in Immunohistochemistry (paraffin-embedded sections).
The MA1-46002 immunogen is a human PMP22 cDNA boosted with a 13-amino acid peptide of the 2nd extracellular domain (residues 120-133) conjugated to mouse IgG.
Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).
PMP22 Antibody (MA1-46002) in IHC MA1-46002_Immunohistochemistry.jpg
Immunohistochemistry with anti-PMP22 Monoclonal Antibody [Hu1] (MA1-46002)