Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Specific Information
PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.
PHLPP2 Antibody (PA5-25995) in WB PHLPP2-_Antibody_PA5-25995_WB_1_112013.jpg
Western Blot with anti-PHLPP2 Polyclonal Antibody (PA5-25995)
Immunohistochemistry analysis in formalin-fixed, paraffin-embedded colon carcinoma using a PHLPP2 polyclonal antibody (Product # PA5-25995), followed by HRP-conjugated secondary antibody and DAB staining.
PHLPP2 Antibody (PA5-25995) in FACS PHLPP2-_Antibody_PA5-25995_FC_1_112013.jpg
Flow Cytometry with anti-PHLPP2 Polyclonal Antibody (PA5-25995)
Flow cytometry analysis of MDA-MB231 cells using a PHLPP2 polyclonal antibody (Product # PA5-25995) (right) compared to a negative control cell (left) at a dilution of 1:10-50, followed by a FITC-conjugated goat anti-rabbit antibody
(This product is for In Vitro experimental use only. Not for resale without express authorization.)