PDX1 Antibody

PDX1 Polyclonal Antibody for Western blot

>> See 4 other antibodies for PDHX (Pyruvate dehydrogenase protein X component, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein)
Synonyms:
Pyruvate dehydrogenase protein X component, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms)
Immunogen: KLH conjugated synthetic peptide between 429-459 amino acids from the C-terminal region of human PDX1
Ordering Information
Pierce PDX1 Antibody
Product #
PA5-11896
Size
400 ul
Price
$316.00
Purchase
Add PDX1 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: Lot-specific
Purification: Antigen affinity chromatography
Storage Buffer: PBS
Preservative: 0.09% sodium azide
Storage Conditions: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Specific Information
General Information
PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.
Product Images
  • PDX1 Antibody (PA5-11896) in WB
    PDX1_Antibody_PA5-11896_WB_3_112013.jpg

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896) (PDX1_Antibody_PA5-11896_WB_3_112013.jpg)

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896)

    Western blot analysis using a PDX1 polyclonal antibody (Product # PA5-11896) in A2058 cell lysates (35ug per lane).
  • PDX1 Antibody (PA5-11896) in WB
    PDX1_Antibody_PA5-11896_WB_2_112013.jpg

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896) (PDX1_Antibody_PA5-11896_WB_2_112013.jpg)

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896)

    Western blot analysis of PDX1 (arrow) using a PDX1 polyclonal antibody (Product # PA5-11896) in 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDX1 gene (Lane 2).
  • PDX1 Antibody (PA5-11896) in WB
    PDX1_Antibody_PA5-11896_WB_1_112013.jpg

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896) (PDX1_Antibody_PA5-11896_WB_1_112013.jpg)

    Western Blot with anti-PDX1 Polyclonal Antibody (PA5-11896)

    Western blot analysis of PDX1 using a PDX1 polyclonal antibody (Product # PA5-11896) in mouse heart tissue lysate.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific