Part of Thermo Fisher Scientific

Osteoprotegerin Polyclonal Antibody

Osteoprotegerin Antibody for Western blot

Synonyms:
MGC29565, OCIF, OPG, TR1
Entrez Gene ID:
(Human) 4982
UniProt ID:
O00300
Details
Host / Isotype: Canine
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: E. Coli His-tagged OPG fusion protein.
Ordering Information
Pierce Osteoprotegerin Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-10526 250 µl $293.00
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This product is not available outside of the U.S.

Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 250 μl of lyophilized antiserum. Redissolving the powder with 250 microliter sterile water will restore to the original concentration.


Applications Dilution *
Western Blot (WB) 1:5,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-10526 detects Osteoprotegerin in human samples.

GB-10526 has been successfully used in Western blot procedures.

The GB-10526 immunogen is a HIS-tagged OPG fusion corresponding to residues 201-401.
General Information
Osteoprotegerin is a member of the TNF receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of the gene have been reported, but their full length nature has not been determined.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)