* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
0.1M tris, pH 7,
10% glycerol, 0.1M glycine
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-28197 targets OTC in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-28197 immunogen is recombinant fragment corresponding to a region within amino acids 80 and 354 of Human OTC.
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
OTC Antibody (PA5-28197) in WB PA5-28197_WB_2.jpg
Western Blot with anti-OTC Polyclonal Antibody (PA5-28197)