Part of Thermo Fisher Scientific

ORF37 Polyclonal Antibody

ORF37 Antibody for ELISA, Western blot

Synonyms:
Protein C35, HBV X-transactivated gene 4 protein
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Human (Hu)
Immunogen: Synthetic peptide corresponding to the N-terminal region of human ORF37.
Ordering Information
Pierce ORF37 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-10486 100 µg $366.00
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This product is not available outside of the U.S.

Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 ug of affinity purified antibody lyophilized from a concentrated (1mg/ml) solution with no additives.


Applications Dilution *
ELISA (ELISA) 1:10,000
Western Blot (WB) 1:5000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-10486 detects ORF37 in human samples.

GB-10486 has been successfully used in ELISA and Western blot procedures.

The GB-10486 immunogen is a synthetic peptide located in the N-terminal of human ORF37.
General Information
During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)