Nurr1 Antibody

Nurr1 Polyclonal Antibody for Western blot, IHC

>> See 3 other antibodies for NR4A2 (NOT; NURR1; TINUR; Nuclear Receptor of T Cells; Nuclear Receptor Related 1; Transcriptionally Inducible Nuclear Receptor; Nuclear Receptor Subfamily 4)
Synonyms:
NOT; NURR1; TINUR; Nuclear Receptor of T Cells; Nuclear Receptor Related 1; Transcriptionally Inducible Nuclear Receptor; Nuclear Receptor Subfamily 4
Entrez Gene ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt)
Immunogen: Synthetic peptide corresponding to an internal sequence (CTERHGLKEPKRVEE) of human Nurr1 protein.
Ordering Information
Pierce Nurr1 Antibody
Product #
PA1-4519
Size
100 µg
Price
$340.00
Purchase
Add Nurr1 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:1000 - 1:2000
Immunohistochemistry (IHC) 1:100 - 1:200
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: Affinity chromatography
Storage Buffer: PBS
Preservative: 0.02% sodium azide
Storage Conditions: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Specific Information
PA1-4519 detects Nurr1 in human, rat, and mouse samples.

PA1-4519 has been successfully used in Western blot and Immunohistochemistry procedures. This antibody is specific for the ~70 kDa protein representing Nurr1.

PA1-4519 immunogen is a synthetic peptide corresponding to an internal sequence (CTERHGLKEPKRVEE) of human Nurr1 protein.

General Information
The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's.
Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis.
Product Images
  • Nurr1 Antibody (PA1-4519) in WB
    PA1-4519_1_07232010.jpg

    Western Blot with anti-Nurr1 Polyclonal Antibody (PA1-4519) (PA1-4519_1_07232010.jpg)

    Western Blot with anti-Nurr1 Polyclonal Antibody (PA1-4519)

    Western blot of human hippocampus tissue lysate showing specific labeling of the ~70 kDa Nurr1 protein.
  • Nurr1 Antibody (PA1-4519) in IF
    NR4A2_Antibody_PA1-4519_Immunofluorescence(IF).jpg

    Immunofluorescence with anti-Nurr1 Polyclonal Antibody (PA1-4519) (NR4A2_Antibody_PA1-4519_Immunofluorescence(IF).jpg)

    Immunofluorescence with anti-Nurr1 Polyclonal Antibody (PA1-4519)

    Immunofluorescent staining of rat brain hippocampus using PA1-4519.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific