Nurr1 Antibody
Nurr1 Polyclonal Antibody for IHC, Western blot
Synonyms:
NOT; NURR1; TINUR; Nuclear Receptor of T Cells; Nuclear Receptor Related 1; Transcriptionally Inducible Nuclear Receptor; Nuclear Receptor Subfamily 4
Entrez Gene ID:
UniProt ID:
(Hu) P43354, (Ms) Q06219, (Rt) Q07917
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Mouse (Ms) Rat (Rt) |
| Immunogen: | Synthetic peptide corresponding to an internal sequence (CTERHGLKEPKRVEE) of human Nurr1 protein. |
| Ordering Information | ||||
| Pierce Nurr1 Antibody |
| Storage: | Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
| Form: | 100 µg affinity purified antibody (1 mg/ml) in PBS with 0.02% sodium azide. |
| Applications | Dilution * |
| Immunohistochemistry (IHC) | 1:100 - 1:200 |
| Western Blot (WB) | 1:1000 - 1:2000 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA1-4519 detects Nurr1 in human, rat, and mouse samples. PA1-4519 has been successfully used in Western blot and Immunohistochemistry procedures. This antibody is specific for the ~70 kDa protein representing Nurr1. PA1-4519 immunogen is a synthetic peptide corresponding to an internal sequence (CTERHGLKEPKRVEE) of human Nurr1 protein. |
| General Information |
| The Nurr1 gene encodes a member of the steroid-thyroid hormone- retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson's. Nurr1 is a stem cell marker and cooperates with PITX3 to promote terminal maturation of murine and human embryonic stem cell cultures to a midbrain dopamine neuron phenotype. In addition, Nurr1 is involved in the regulation of corticotropin-releasing hormone (CRH), which may be linked to and associated with rheumatoid arthritis. |
| Product Images |
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Nurr1 Antibody (PA1-4519) in IF
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Immunofluorescence with anti-Nurr1 Polyclonal Antibody (PA1-4519)
Immunofluorescent staining of rat brain hippocampus using PA1-4519. -
Nurr1 Antibody (PA1-4519) in WB
Western Blot with anti-Nurr1 Polyclonal Antibody (PA1-4519)
Western blot of human hippocampus tissue lysate showing specific labeling of the ~70 kDa Nurr1 protein.
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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Nurr1 Antibodies > Nurr1 Polyclonal Antibody PA1-4519
