Neurofibromin 2 Antibody

Neurofibromin 2 Polyclonal Antibody for Western blot, IHC (P)

>> See 6 other antibodies for NF2 (ACN, BANF, SCH, merlin, moesin-ezrin-radixin like, moesin-ezrin-radixin-like protein, moesin-ezrin-radizin-like protein, neurofibromin 2 (bilateral acoustic neuroma), neurofibromin-2, schwannomerlin, schwannomin)
Synonyms:
ACN, BANF, SCH, merlin, moesin-ezrin-radixin like, moesin-ezrin-radixin-like protein, moesin-ezrin-radizin-like protein, neurofibromin 2 (bilateral acoustic neuroma), neurofibromin-2, schwannomerlin, schwannomin
Entrez Gene ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt)
Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 172 of Human Neurofibromin 2
Ordering Information
Pierce Neurofibromin 2 Antibody
Product #
PA5-29748
Size
100 µL
Price
$324.00
Purchase
Tested Applications Dilution *
Western Blot (WB) 1:1000-1:10,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: 0.1M tris, pH 7, with 20% glycerol, 0.1M glycine
Preservative: 0.01% thimerosal
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-29748 targets Neurofibromin 2 in IHC (P) and WB applications and shows reactivity with Human, mouse, and Rat samples.

The PA5-29748 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 172 of Human Neurofibromin 2.
General Information
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Product Images
  • Neurofibromin 2 Antibody (PA5-29748) in WB
    PA5-29748_WB_1.jpg

    Western Blot with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748) (PA5-29748_WB_1.jpg)

    Western Blot with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748)

    Western blot analysis of Neurofibromin 2 using 20µg of mouse brain lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a Neurofibromin 2 polyclonal antibody (Product # PA5-29748) at a dilution of 1:10,000.
  • Neurofibromin 2 Antibody (PA5-29748) in WB
    PA5-29748_WB_2.jpg

    Western Blot with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748) (PA5-29748_WB_2.jpg)

    Western Blot with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748)

    Western blot analysis of Neurofibromin 2 using 30µg of A) A431 (B) H1299 and C) HeLa lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a Neurofibromin 2 polyclonal antibody (Product # PA5-29748) at a dilution of 1:1000.
  • Neurofibromin 2 Antibody (PA5-29748) in IHC (P)
    PA5-29748_IHC_1.jpg

    Immunohistochemistry (Paraffin) with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748) (PA5-29748_IHC_1.jpg)

    Immunohistochemistry (Paraffin) with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748)

    Immunohistochemical analysis of Neurofibromin 2 in paraffin-embedded gastric carcinoma using a Neurofibromin 2 polyclonal antibody (Product # PA5-29748) at a dilution of 1:500.
  • Neurofibromin 2 Antibody (PA5-29748) in IHC (P)
    PA5-29748_IHC_2.jpg

    Immunohistochemistry (Paraffin) with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748) (PA5-29748_IHC_2.jpg)

    Immunohistochemistry (Paraffin) with anti-Neurofibromin 2 Polyclonal Antibody (PA5-29748)

    Immunohistochemical analysis of Neurofibromin 2 in paraffin-embedded RT2 xenograft using a Neurofibromin 2 polyclonal antibody (Product # PA5-29748) at a dilution of 1:500.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific