Part of Thermo Fisher Scientific

Nebulin Monoclonal Antibody (NB2)

Nebulin Antibody for IF, Western blot

Synonyms:
DKFZp686C1456, FLJ11505, FLJ36536, FLJ39568, FLJ39584, NEB177D, NEM2
Entrez Gene ID:
(Human) 4703, (Murine) 17996, (Rat) 311029, (Bovine) 407121
UniProt ID:
P20929
Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: NB2
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt) Rabbit (Rb) Bovine (Bv) Porcine (Po) Chicken (Ck) Amphibian (Am) Fish (Fs) Avian (Av) Reptile (Rp)
Immunogen: Purified, full length, native chicken protein.
Ordering Information
Pierce Nebulin Monoclonal Antibody (NB2)
Product Number Pkg. Size Price Purchase
MA1-24951 100 µl $327.00
Add Nebulin Monoclonal Antibody (NB2) to your cart.


Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: 100 µl of ascites antibody with 0.1% sodium azide.


Applications Dilution *
Western Blot (WB) Assay Dependent
Immunofluorescence (IF) 1:400
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA1-24951 detects Nebulin from chicken, mouse rat, rabbit, bovine, porcine, human, salamander, pigeon, alligator, toad, and fish samples. This antibody reacts only with skeletal muscle, and does not react with smooth muscle or non-muscle cell cultures. This antibody does not cross-react with Titin.

MA1-24951 has been successfully used in Western blot procedures.

The MA1-24951 immunogen is purified, full length, native chicken protein.
General Information
This gene encodes nebulin, a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates, nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue-, species-,and developmental stage-specific. Of the 183 exons in the nebulin gene, at least 43 are alternatively spliced, although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin, the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)