NFKB1 Antibody

(This product has been discontinued.)
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>> See 15 other antibodies for NFKB1

NFKB1 Polyclonal Antibody for Western blot

>> See 15 other antibodies for NFKB1 (KBF1, EBP1, NF-kappa-B)
Synonyms:
KBF1, EBP1, NF-kappa-B
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Non-human primate (Nhp)
Immunogen: NFkB 1
Ordering Information
Pierce NFKB1 Antibody
Product #
82387
Size
100 ul
Price
$264.00
Purchase
(DISCONTINUED)
Tested Applications Dilution *
Western Blot (WB) 1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form information is not available for this product.
Product Specific Information
82387 targets NFKB1 in WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples.

The 82387 immunogen is nFkB 1.

82387 detects NFKB1 which has a predicted molecular weight of approximately 105, 50 kDa.
General Information
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.
Product Images
  • NFKB1 Antibody (82387) in WB
    82387.jpg

    Western Blot with anti-NFKB1 Polyclonal Antibody (82387) (82387.jpg)

    Western Blot with anti-NFKB1 Polyclonal Antibody (82387)

    A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus NFKB1 siRNA (Lane 3). Western blot data for GAPDH is included as a control for equal protein loading.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific