MMP-10 (Stromelysin-2) Antibody (IVC5)

MMP-10 (Stromelysin-2) Monoclonal Antibody for Western blot, IP

>> See 6 other antibodies for MMP10 (MMP-10, matrix metalloprotease 10, matrix metalloproteinase 10 (stromelysin 2), matrix metalloproteinase-10, stromelysin 2, stromelysin-2, transin 2, transin-2)
Synonyms:
MMP-10, matrix metalloprotease 10, matrix metalloproteinase 10 (stromelysin 2), matrix metalloproteinase-10, stromelysin 2, stromelysin-2, transin 2, transin-2
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Mouse / IgG2b
Class: Monoclonal
Type: Antibody
Clone: IVC5
Tested Species Reactivity: Human (Hu)
Published Species Reactivity: Human (Hu), Rat (Rt)
Immunogen: Human recombinant MMP-10 (stromelysin-2 protein)
Ordering Information
Pierce MMP-10 (Stromelysin-2) Antibody (IVC5)
Product #
MA5-14233
Size
500 ul
Price
$316.00
Purchase
Add MMP-10 (Stromelysin-2) Antibody (IVC5) to your cart.
Tested Applications Dilution *
Western Blot (WB) 1-2 µg/ml
Immunoprecipitation (IP) 2 µg/ml
Published Applications Dilution
Immunohistochemistry (IHC) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.2mg/ml
Purification: Protein A
Storage Buffer: PBS, pH 7.4, with 0.2% BSA
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
MA5-14233 targets MMP-10 (Stromelysin-2) in IP and WB applications and shows reactivity with Human samples.

The MA5-14233 immunogen is human recombinant MMP-10 (stromelysin-2 protein).
General Information
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading extracellular matrix. Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The two forms of stromelysin (SL), types 1 (MMP-3) and 2 (MMP-10), share 82% sequence homology, but exhibit differences in cellular synthesis and inducibility by cytokines and growth factors in vitro.
Product Images
  • MMP-10 (Stromelysin-2) Antibody (MA5-14233) in WB
    MA5-14233_WesternBlot.jpg

    Western Blot with anti-MMP-10 (Stromelysin-2) Monoclonal Antibody [IVC5] (MA5-14233) (MA5-14233_WesternBlot.jpg)

    Western Blot with anti-MMP-10 (Stromelysin-2) Monoclonal Antibody [IVC5] (MA5-14233)

    Western blot of MMP-10 (Stromelysin-2) using MMP-10 (Stromelysin-2) Monoclonal Antibody (MA5-14233) on U937 Cells.
  • MMP-10 (Stromelysin-2) Antibody (MA5-14233) in IP
    MA5-14233_Immunoprecipitation.jpg

    Immunoprecipitation with anti-MMP-10 (Stromelysin-2) Monoclonal Antibody [IVC5] (MA5-14233) (MA5-14233_Immunoprecipitation.jpg)

    Immunoprecipitation with anti-MMP-10 (Stromelysin-2) Monoclonal Antibody [IVC5] (MA5-14233)

    Immunoprecipitation of MMP-10 (Stromelysin-2) using MMP-10 (Stromelysin-2) Monoclonal Antibody (MA5-14233) on Native Human U937 Cells.
Publications:
Immunohistochemistry
  Species / Dilution Summary
  Hu / 0
MA5-14233 was used in immunohistochemistry to study changes in corneal extracellular matrix and MMPs following complicated laser-assisted in situ keratomileusis

Cornea. 2002 Jan;21(1):95-100.
"Extracellular matrix and matrix metalloproteinase changes in human corneas after complicated laser-assisted in situ keratomileusis (LASIK)."
Author(s): Maguen E, Zorapapel NC, Zieske JD, Ninomiya Y, Sado Y, Kenney MC, Ljubimov AV
Number of Citations: 4
(See PubMed article )
  Hu / 2 ug/ml
MA5-14233 was used in immunohistochemistry to investigate the expression and the role of matrix metalloproteinases in intestinal fistulae

Gut. 2004 May;53(5):701-9.
"Expression and localisation of matrix metalloproteinases and their natural inhibitors in fistulae of patients with Crohn's disease."
Author(s): Kirkegaard T, Hansen A, Bruun E, Brynskov J
Number of Citations: 8
(See PubMed article )
  Rt / 1:500
MA5-14233 was used in immunohistochemistry to study fibrosis and fibrotic nodule formation following silica inhalation and the role of MMPs

Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L709-17.
"Matrix metalloproteinase induction in fibrosis and fibrotic nodule formation due to silica inhalation."
Author(s): Scabilloni JF, Wang L, Antonini JM, Roberts JR, Castranova V, Mercer RR
Number of Citations: 4
(See PubMed article )
  Rt / 1:500
MA5-14233 was used in immunohistochemistry to study the ability of cerium oxide nanoparticles to induce pulmonary fibrosis in a rat model

Toxicol Appl Pharmacol. 2012 Aug 1;262(3):255-64.
"Induction of pulmonary fibrosis by cerium oxide nanoparticles."
Author(s): Ma JY, Mercer RR, Barger M, Schwegler-Berry D, Scabilloni J, Ma JK, Castranova V
Number of Citations: 4
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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