* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Ammonium sulfate precipitation
PBS, pH 7.4,
0.09% sodium azide
Product Specific Information
MA5-14627 targets CD115 in IF and IHC (F) applications and shows reactivity with Human samples.
The MA5-14627 immunogen is a v-ras-transformed rat NRK cells expressing transduced human CSF-1R.
CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)