K-Ras Antibody

K-Ras Polyclonal Antibody for Western blot, IF, ICC, IHC (P), IP, ELISA

>> See 2 other antibodies for KRAS (C-K-RAS, RASK, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, RASK2, GTPase KRas, K-Ras 2, K-ras p21 protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, PR310 c-K-ras oncogene, c-Ki-ras, c-Kirsten-ras protein, cellular c-Ki-ras2)
Synonyms:
C-K-RAS, RASK, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, RASK2, GTPase KRas, K-Ras 2, K-ras p21 protein, Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog, PR310 c-K-ras oncogene, c-Ki-ras, c-Kirsten-ras protein, cellular c-Ki-ras2
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 73 of Human K-Ras
Ordering Information
Pierce K-Ras Antibody
Product #
PA5-27234
Size
100 ul
Price
$316.00
Purchase
Add K-Ras Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:500-1:3000
Immunofluorescence (IF) 1:100-1:1000
Immunocytochemistry (ICC) 1:100-1:1000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
Immunoprecipitation (IP) Assay Dependent
ELISA (ELISA) Assay Dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS, pH 7, with 20% glycerol
Preservative: 0.025% Proclin 300
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-27234 targets K-Ras in IF, IHC (P), ELISA, IP and WB applications and shows reactivity with Human samples.

The PA5-27234 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 73 of Human K-Ras.
General Information
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.
Product Images
  • K-Ras Antibody (PA5-27234) in WB
    K-Ras_PA5-27234_Antibody_WesternBlot.jpg

    Western Blot with anti-K-Ras Polyclonal Antibody (PA5-27234) (K-Ras_PA5-27234_Antibody_WesternBlot.jpg)

    Western Blot with anti-K-Ras Polyclonal Antibody (PA5-27234)

    Western Blot analysis of K-Ras using anti-K-Ras Polyclonal Antibody (PA5-27234), in HCT116 Cell Lysate (30 ug of cell lysate) and at a dilution of 1:1000.
  • K-Ras Antibody (PA5-27234) in IF
    K-Ras_PA5-27234_Antibody_Immunofluorescence.jpg

    Immunofluorescence with anti-K-Ras Polyclonal Antibody (PA5-27234) (K-Ras_PA5-27234_Antibody_Immunofluorescence.jpg)

    Immunofluorescence with anti-K-Ras Polyclonal Antibody (PA5-27234)

    Immunofluorescence analysis of methanol-fixed HeLa cells using K-Ras (PA5-27234) antibody at 1:200 dilution.
  • K-Ras Antibody (PA5-27234) in IHC
    K-Ras_PA5-27234_Antibody_Immunohistochemistry.jpg

    Immunohistochemistry with anti-K-Ras Polyclonal Antibody (PA5-27234) (K-Ras_PA5-27234_Antibody_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-K-Ras Polyclonal Antibody (PA5-27234)

    Immunohistochemical analysis of paraffin-embedded U373 xenograft using K-Ras antibody (PA5-27234) antibody at 1:500 dilution.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific