ITM2B Antibody

ITM2B Polyclonal Antibody for Western blot, IF, ICC, IHC (P)

>> See 2 other antibodies for ITM2B (ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, ABri/ADan amyloid peptide, BRICHOS domain containing 2B, transmembrane protein BRI)
Synonyms:
ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, ABri/ADan amyloid peptide, BRICHOS domain containing 2B, transmembrane protein BRI
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms)
Immunogen: Recombinant fragment corresponding to a region within amino acids 15 and 264 of Human ITM2B
Ordering Information
Pierce ITM2B Antibody
Product #
PA5-31441
Size
100 ul
Price
$316.00
Purchase
Add ITM2B Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:500-1:3000
Immunofluorescence (IF) 1:100-1:1000
Immunocytochemistry (ICC) 1:100-1:1000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.93mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS, pH 7, with 1% BSA, 20% glycerol
Preservative: 0.01% thimerosal
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-31441 targets ITM2B in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.

The PA5-31441 immunogen is recombinant fragment corresponding to a region within amino acids 15 and 264 of Human ITM2B.
General Information
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Product Images
  • ITM2B Antibody (PA5-31441) in WB
    ITM2B_PA5-31441_Antibody_WesternBlot.jpg

    Western Blot with anti-ITM2B Polyclonal Antibody (PA5-31441) (ITM2B_PA5-31441_Antibody_WesternBlot.jpg)

    Western Blot with anti-ITM2B Polyclonal Antibody (PA5-31441)

    Western Blot analysis of ITM2B using anti-ITM2B Polyclonal Antibody (PA5-31441), in Mouse Brain (50 ug of cell lysate) and at a dilution of 1:1000.
  • ITM2B Antibody (PA5-31441) in WB
    ITM2B_PA5-31441_Antibody_WesternBlot_2.jpg

    Western Blot with anti-ITM2B Polyclonal Antibody (PA5-31441) (ITM2B_PA5-31441_Antibody_WesternBlot_2.jpg)

    Western Blot with anti-ITM2B Polyclonal Antibody (PA5-31441)

    Western Blot analysis using anti-ITM2B Polyclonal Antibody on the following cells: (30 ug of whole cell lysate) A: Hep G2 cell lysate B: HCT116. Primary antibody (PA5-31441) diluted at 1:1000
  • ITM2B Antibody (PA5-31441) in IF
    ITM2B_PA5-31441_Antibody_Immunofluorescence.jpg

    Immunofluorescence with anti-ITM2B Polyclonal Antibody (PA5-31441) (ITM2B_PA5-31441_Antibody_Immunofluorescence.jpg)

    Immunofluorescence with anti-ITM2B Polyclonal Antibody (PA5-31441)

    Immunofluorescence analysis of methanol-fixed HeLa cells using ITM2B (PA5-31441) antibody at 1:200 dilution.
  • ITM2B Antibody (PA5-31441) in IHC
    ITM2B_PA5-31441_Antibody_Immunohistochemistry.jpg

    Immunohistochemistry with anti-ITM2B Polyclonal Antibody (PA5-31441) (ITM2B_PA5-31441_Antibody_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-ITM2B Polyclonal Antibody (PA5-31441)

    Immunohistochemical analysis of paraffin-embedded U373 xenograft using ITM2B (PA5-31441) antibody at 1:500 dilution.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific