IL-4 Antibody

IL-4 Polyclonal Antibody for Western blot, ELISA

>> See 23 other antibodies for IL4 (B-cell stimulatory factor 1; BSF-1; IL-4; interleukin-4; lymphocyte stimulatory factor 1)
Synonyms:
B-cell stimulatory factor 1; BSF-1; IL-4; interleukin-4; lymphocyte stimulatory factor 1
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Bovine (Bv)
Published Species Reactivity: Bovine (Bv)
Immunogen: Recombinant bovine IL-4
Ordering Information
Pierce IL-4 Antibody
Product #
PBOIL4I
Size
1 mg
Price
$250.00
Purchase
Add IL-4 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) Assay Dependent
ELISA (ELISA) Assay Dependent
Published Applications Dilution
ELISA (ELISA) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Lyophilized
Purification: Protein G
Storage Buffer: PBS
Preservative: no preservative
Storage Conditions: 4° C
Product Specific Information
PBOIL4I targets IL-4 in ELISA, and WB applications and shows reactivity with Bovine samples.

The PBOIL4I immunogen is recombinant bovine IL-4.

PBOIL4I detects IL-4 which has a predicted molecular weight of approximately 13 kDa.
General Information
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Publications:
ELISA
  Species / Dilution Summary
  Bv / Not Cited
PBOIL4I was used in ELISA to evaluate the diagnostic markers of Mycobacterium bovis infection in cattle

Clin Vaccine Immunol. 2010 Dec;17(12):1946-51.
"Simultaneous measurement of antigen-stimulated interleukin-1 beta and gamma interferon production enhances test sensitivity for the detection of Mycobacterium bovis infection in cattle."
Author(s): Jones GJ, Pirson C, Hewinson RG, Vordermeier HM
Number of Citations: 4
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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