IL-4 Antibody
IL-4 Polyclonal Antibody for ELISA, Western blot
Synonyms:
B-cell stimulatory factor 1; BSF-1; IL-4; interleukin-4; lymphocyte stimulatory factor 1
Entrez Gene ID:
UniProt ID:
P30367
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Bovine (Bv) |
| Immunogen: | Recombinant bovine IL-4 |
| Ordering Information | ||||
| Pierce IL-4 Antibody |
| Storage: | 4° C |
| Form: | 1 mg of purified antibody from mouse ascites fluid by Protein G affinity chromatography and Lyophilized in PBS, without preservative or carrier protein |
| Applications | Dilution * |
| ELISA (ELISA) | Assay Dependent |
| Western Blot (WB) | Assay Dependent |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PBOIL4I targets IL-4 in ELISA, and WB applications and shows reactivity with Bovine samples. The PBOIL4I immunogen is recombinant bovine IL-4. PBOIL4I detects IL-4 which has a predicted molecular weight of approximately 13 kDa. |
| General Information |
| The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| PubMed References: |
| ELISA | ||
| Species / Dilution | Summary | |
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Bv / Not Cited |
PBOIL4I was used in ELISA to evaluate the diagnostic markers of Mycobacterium bovis infection in cattle
Clin Vaccine Immunol. 2010 Dec;17(12):1946-51.
"Simultaneous measurement of antigen-stimulated interleukin-1 beta and gamma interferon production enhances test sensitivity for the detection of Mycobacterium bovis infection in cattle." Author(s): Jones GJ, Pirson C, Hewinson RG, Vordermeier HM Number of Citations: 4 (See PubMed article  )
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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IL-4 Antibodies > IL-4 Polyclonal Antibody PBOIL4I
