IL-1 beta Antibody

IL-1 beta Polyclonal Antibody for Western blot

>> See 16 other antibodies for IL1B (IL-1 beta; interleukin-1 beta; prointerleukin-1 beta)
Synonyms:
IL-1 beta; interleukin-1 beta; prointerleukin-1 beta
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Porcine (Po)
Immunogen: Recombinant porcine IL-1 beta
Ordering Information
Pierce IL-1 beta Antibody
Product #
PP425
Size
1 mg
Price
$280.00
Purchase
Add IL-1 beta Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) Assay Dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.67mg/ml
Purification: Protein A
Storage Buffer: PBS
Preservative: no preservative
Storage Conditions: -20°C
Product Specific Information
PP425 targets IL-1 beta in WB applications and shows reactivity with Porcine samples.

The PP425 immunogen is recombinant porcine IL-1 beta.

PP425 detects IL-1 beta which has a predicted molecular weight of approximately 18 kDa.
General Information
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific