IL-1 beta Antibody
IL-1 beta Polyclonal Antibody for Western blot
Synonyms:
IL-1 beta; interleukin-1 beta; prointerleukin-1 beta
Entrez Gene ID:
UniProt ID:
P26889
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Porcine (Po) |
| Immunogen: | Recombinant porcine IL-1 beta |
| Ordering Information | ||||
| Pierce IL-1 beta Antibody |
| Storage: | -20°C |
| Form: | 1 mg of purified antibody from rabbit serum by protein A affinity chromatography; in PBS without preservatives |
| Applications | Dilution * |
| Western Blot (WB) | Assay Dependent |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PP425 targets IL-1 beta in WB applications and shows reactivity with Porcine samples. The PP425 immunogen is recombinant porcine IL-1 beta. PP425 detects IL-1 beta which has a predicted molecular weight of approximately 18 kDa. |
| General Information |
| The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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IL-1 beta Antibodies > IL-1 beta Polyclonal Antibody PP425
