IL-1 beta Antibody

IL-1 beta Polyclonal Antibody for ELISA

>> See 16 other antibodies for IL1B (IL-1 beta; interleukin-1 beta)
Synonyms:
IL-1 beta; interleukin-1 beta
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Bovine (Bv)
Published Species Reactivity: Bovine (Bv)
Immunogen: Recombinant IL-1 beta
Ordering Information
Pierce IL-1 beta Antibody
Product #
PBOIL1BI
Size
1 mg
Price
$250.00
Purchase
Add IL-1 beta Antibody to your cart.
Tested Applications Dilution *
ELISA (ELISA) Assay Dependent
Published Applications Dilution
ELISA (ELISA) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Lyophilized
Purification: Protein G
Preservative: no preservative
Storage Conditions: 4° C
Product Specific Information
PBOIL1BI targets IL-1 beta in ELISA applications and shows reactivity with Bovine samples.

The PBOIL1BI immunogen is recombinant IL-1 beta.

PBOIL1BI detects IL-1 beta which has a predicted molecular weight of approximately 18 kDa.
General Information
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Publications:
ELISA
  Species / Dilution Summary
  Bv / 5 ug/ml
PBOIL1BI was used in ELISA to investigate the inflammatory response to a bovine intramammary challenge with a persistent strain of Escherichia coli during late gestation

J Dairy Sci. 2012 Jan;95(1):117-26.
"Bovine intramammary Escherichia coli challenge infections in late gestation demonstrate a dominant antiinflammatory immunological response."
Author(s): Quesnell RR, Klaessig S, Watts JL, Schukken YH
Number of Citations: 0
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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