IL-1 beta Antibody, Biotin conjugate
IL-1 beta Polyclonal Antibody for ELISA
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Label: | Biotin |
| Species Reactivity: | Bovine (Bv) |
| Immunogen: | Recombinant Bovine IL-1 beta |
| Ordering Information | ||||
| Pierce IL-1 beta Antibody, Biotin conjugate |
| Storage: | 4° C |
| Form: | 250 ug of purified antibody by Protein G affinity chromatography then Lyophilized, preservative and carrier free |
| Applications | Dilution * |
| ELISA (ELISA) | Assay Dependent |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PBOIL1BBI targets IL-1 beta in ELISA applications and shows reactivity with Bovine samples. The PBOIL1BBI immunogen is recombinant Bovine IL-1 beta. PBOIL1BBI detects IL-1 beta which has a predicted molecular weight of approximately 18 kDa. |
| General Information |
| The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| PubMed References: |
| ELISA | ||
| Species / Dilution | Summary | |
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Bv / 5 ug/ml |
PBOIL1BBI was used in ELISA to investigate the inflammatory response to a bovine intramammary challenge with a persistent strain of Escherichia coli during late gestation
J Dairy Sci. 2012 Jan;95(1):117-26.
"Bovine intramammary Escherichia coli challenge infections in late gestation demonstrate a dominant antiinflammatory immunological response." Author(s): Quesnell RR, Klaessig S, Watts JL, Schukken YH Number of Citations: 0 (See PubMed article  )
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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IL-1 beta Antibodies > IL-1 beta Polyclonal Antibody PBOIL1BBI
