HEXA Antibody (3F10)

HEXA Monoclonal Antibody for Western blot, FACS

Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Mouse / IgG2b
Class: Monoclonal
Type: Antibody
Clone: 3F10
Tested Species Reactivity: Human (Hu), Mouse (Ms)
Immunogen: Purified recombinant fragment of human HEXA expressed in E. Coli.
Ordering Information
Pierce HEXA Antibody (3F10)
Product #
MA5-17089
Size
100 ug
Price
$310.00
Purchase
Add HEXA Antibody (3F10) to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:500 - 1:2000
Flow Cytometry (FACS) 1:200 - 1:400
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1mg/ml
Purification: purified
Storage Buffer: PBS with 0.5% proprietary stabilizer
Preservative: 0.05% sodium azide
Storage Conditions: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
MA5-17089 targets HEXA in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.

The MA5-17089 immunogen is purified recombinant fragment of human HEXA expressed in E. Coli.

MA5-17089 detects HEXA which has a predicted molecular weight of approximately 60.7kDa.
General Information
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Product Images
  • HEXA Antibody (MA5-17089) in WB
    HEXA_Antibody_MA5-17089_Westernblot1-1252013.jpg

    Western Blot with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089) (HEXA_Antibody_MA5-17089_Westernblot1-1252013.jpg)

    Western Blot with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089)

    Western blot analysis of HEXA using a HEXA monoclonal antibody (Product # MA5-17089) against a human HEXA (AA: 29-181) recombinant protein.
  • HEXA Antibody (MA5-17089) in WB
    HEXA_Antibody_MA5-17089_Westernblot2-1252013.jpg

    Western Blot with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089) (HEXA_Antibody_MA5-17089_Westernblot2-1252013.jpg)

    Western Blot with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089)

    Western blot analysis of HEXA using HEXA monoclonal antibody (Product # MA5-17089) in L1210 (1), and HL7702 (2) cell lysate.
  • HEXA Antibody (MA5-17089) in FACS
    HEXA_Antibody_MA5-17089_FlowCytometry-1252013.jpg

    Flow Cytometry with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089) (HEXA_Antibody_MA5-17089_FlowCytometry-1252013.jpg)

    Flow Cytometry with anti-HEXA Monoclonal Antibody [3F10] (MA5-17089)

    Flow cytometric analysis of HeLa cells using HEXA monoclonal antibody (Product # MA5-17089) (green) and negative control (red).
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific