* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
0.05% sodium azide
-20°C or -80°C if preferred
Product Specific Information
This antibody is predicted to react with rat based on 100% sequence homology.
Glucose Transporter 4 (GLUT4/SLC2A4) is a member of a family of proteins that facilitate glucose transport. In response to insulin GLUT4 translocates from low density microsomes to the plasma membrane. Activation of phosphatidylinositol-3-OH kinase is required for this trafficking event but is not sufficient. Insulin resistant subjects with and without diabetes show abnormal accumulation of GLUT4 in a dense membrane compartment in muscle and adipocytes from which insulin is unable to recruit GLUT4 to the cell surface.
Glucose Transporter GLUT4 Antibody (PA5-23052) in WB PA5-23052_WesternBlot.jpg
Western Blot with anti-Glucose Transporter GLUT4 Polyclonal Antibody (PA5-23052)