Part of Thermo Fisher Scientific

Gelsolin Monoclonal Antibody (20)

Gelsolin Antibody for ELISA, Western blot

Synonyms:
Actin-depolymerizing factor, ADFBrevin, AGEL
Entrez Gene ID:
(Human) 2934
UniProt ID:
P06396
Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: 20
Species Reactivity: Human (Hu)
Immunogen: Gelsolin purified from human plasma.
Ordering Information
Pierce Gelsolin Monoclonal Antibody (20)
Product Number Pkg. Size Price Purchase
ABS 017-20-02 200 µl $532.00
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Storage: 4º C, store in dark
Form: 200 ul of protein A/G purified antibody (1 mg/ml) in 0.01 M phosphate buffer with 0.5 M NaCl and 15 mM sodium azide; pH 7.4.


Applications Dilution *
ELISA (ELISA) 1:4000
Western Blot (WB) Assay dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
ABS 017-20-02 detects Gelsolin from human samples.

ABS 017-20-02 has been successfully used in ELISA and western blot procedures. ABS 017-20-02 does not work as capture antibody in sandwich ELISA.

The ABS 017-20-02 immunogen is a Gelsolin protein purified from human plasma.
General Information
Gelsolin participates in the extracellular actin scavenger system, binding actin and disaggregating filamentous actin released from dying cells. Actin monomers are then transferred to Gc-globulin. The plasma concentration of gelsolin is reduced in conditions of major actin release, such as acute liver failure, major trauma and rhabdomyolysis, where multi-organ failure is a risk. It has been suggested that gelsolin, like Gc-globulin, can be a prognostic factor in these conditions.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)