* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
0.1M tris, pH 7,
10% glycerol, 0.1M glycine
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-27350 targets Gelsolin in IF, IHC (P), and WB applications and shows reactivity with Human, rat, and mouse samples.
The PA5-27350 immunogen is recombinant fragment corresponding to a region within amino acids 561 and 782 of Human Gelsolin.
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Gelsolin Antibody (PA5-27350) in WB Gelsolin_PA5-27350_Antibody_WesternBlot.jpg
Western Blot with anti-Gelsolin Polyclonal Antibody (PA5-27350)