Gastric Mucin Antibody (45M1)

Printable Datasheet

 

View 127 References

Gastric Mucin Monoclonal Antibody for ICC, IHC (P), Western blot

Ordering Information

Pierce Gastric Mucin Antibody (45M1)

Product #

MA1-25073

Size

200 µl

Price

$354.00

Purchase

Bulk Order?

Storage:	-20° C, Avoid Freeze/Thaw Cycles
Form:	200 ul of unpurified antibody with 0.1% sodium azide.

PubMed References:

• BLOCK (2)
• ELISA (32)
• FACS (2)
• ICC (22)
• IHC (52)
• IP (1)
• WB (16)

Blocking Assay
	Species / Dilution	Summary
	Hu / Not Cited	MA1-25073 was used in blocking or activating experiment and immunocytochemistry to examine the involvement of coagulation factor Xa in the pathogenesis of asthma Am J Respir Crit Care Med. 2007 Jan 15;175(2):136-43. "Coagulation factor Xa modulates airway remodeling in a murine model of asthma." Author(s): Shinagawa K, Martin JA, Ploplis VA, Castellino FJ Number of Citations: 6 (See PubMed article )
	Hu / 0	MA1-25073 was used in blocking or activating experiment to investigate the role of coagulation factor VIIa in the asthmatic response in mice Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L763-70. "A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice." Author(s): Shinagawa K, Ploplis VA, Castellino FJ Number of Citations: 1 (See PubMed article )

ELISA
	Species / Dilution	Summary
	GP / 0	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the differential expression and secretion of Muc2 and Muc5ac in guinea pig tracheal epithelial cells Respir Res. 2006 Feb 25;7():35. "Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro." Author(s): Chorley BN, Crews AL, Li Y, Adler KB, Minnicozzi M, Martin LD Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA to investigate the effect of azithromycin on MUC5AC production in NCI-H292 cells Antimicrob Agents Chemother. 2004 Sep;48(9):3457-61. "Azithromycin inhibits MUC5AC production induced by the Pseudomonas aeruginosa autoinducer N-(3-Oxododecanoyl) homoserine lactone in NCI-H292 Cells." Author(s): Imamura Y, Yanagihara K, Mizuta Y, Seki M, Ohno H, Higashiyama Y, Miyazaki Y, Tsukamoto K, Hirakata Y, Tomono K, Kadota J, Kohno S Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in ELISA to investigate the effect of PMA on MUC5AC respiratory mucin J Mol Biol. 2004 Nov 26;344(3):683-95. "PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanisms." Author(s): Hewson CA, Edbrooke MR, Johnston SL Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the influence of PDE4 inhibition on mucin expression in human airway epithelial cells Thorax. 2005 Feb;60(2):144-52. "Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells." Author(s): Mata M, Sarriá B, Buenestado A, Cortijo J, Cerdá M, Morcillo EJ Number of Citations: 10 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA to study the effect of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in MUC5AC expression in non-small cell lung cancer cells Lung Cancer. 2005 Oct;50(1):19-24. "Gefitinib inhibits MUC5AC synthesis in mucin-secreting non-small cell lung cancer cells." Author(s): Kitazaki T, Soda H, Doi S, Nakano H, Nakamura Y, Kohno S Number of Citations: 0 (See PubMed article )
	Hu / 1:10	MA1-25073 was used in ELISA to study the effect of human neutrophil elastase on mucin secretion from human bronchial epithelial cells in vitro Am J Pathol. 2005 Sep;167(3):651-61. "Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism." Author(s): Park JA, He F, Martin LD, Li Y, Chorley BN, Adler KB Number of Citations: 25 (See PubMed article )
	Hu / Not Cited	MA1-25073 was used in ELISA to investigate the influence of cigarette smoke extract on the defence mechanisms of T-cells and epithelial cells Respir Med. 2006 May;100(5):818-27. "Cigarette smoke extract modulates respiratory defence mechanisms through effects on T-cells and airway epithelial cells." Author(s): Glader P, Möller S, Lilja J, Wieslander E, Löfdahl CG, von Wachenfeldt K Number of Citations: 1 (See PubMed article )
	Hu / 0.5 ug/ml	MA1-25073 was used in ELISA to investigate the role of human airway trypsin-like protease in the release of amphiregulin by human airway epithelial cells FEBS J. 2005 Dec;272(24):6387-99. "Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF alpha-converting enzyme activity in airway epithelial cells." Author(s): Chokki M, Eguchi H, Hamamura I, Mitsuhashi H, Kamimura T Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in ELISA and immunohistochemistry to investigate the overproduction of MUC5AC in gallstone disease and its mechanism Am J Pathol. 2006 Dec;169(6):2031-41. "MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder." Author(s): Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA to study the role of IkappaB kinases in MUC5AC mucin induction by Streptococcus pneumoniae J Immunol. 2007 Feb 1;178(3):1736-47. "A novel role for IkappaB kinase (IKK) alpha and IKKbeta in ERK-dependent up-regulation of MUC5AC mucin transcription by Streptococcus pneumoniae." Author(s): Ha U, Lim JH, Jono H, Koga T, Srivastava A, Malley R, Pagès G, Pouysségur J, Li JD Number of Citations: 11 (See PubMed article )
	Hu / Not Cited	MA1-25073 was used in ELISA to investigate the role of MUC5AC on bronchoconstriction pathogenesis J Allergy Clin Immunol. 2007 May;119(5):1092-8. "Role of MUC5AC in the pathogenesis of exercise-induced bronchoconstriction." Author(s): Hallstrand TS, Debley JS, Farin FM, Henderson WR Jr Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA and immunocytochemistry to study the role of the hCLCA1 pathway in the induction of MUC5AC expression by histamine Pharmacology. 2007;80(4):219-26. "Histamine induces MUC5AC expression via a hCLCA1 pathway." Author(s): Kim YM, Won TB, Kim SW, Min YG, Lee CH, Rhee CS Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA to investigate the involvement of PAR-2 in mucin hypersecretion by human bronchial epithelial cells Int J Biochem Cell Biol. 2008;40(6-7):1379-88. "Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro." Author(s): Lin KW, Park J, Crews AL, Li Y, Adler KB Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA to study the mechanism by which MUC5AC mucin transcription is induced by Streptococcus pneumoniae pneumolysin J Biol Chem. 2008 Nov 7;283(45):30624-31. "MKP1 regulates the induction of MUC5AC mucin by Streptococcus pneumoniae pneumolysin by inhibiting the PAK4-JNK signaling pathway." Author(s): Ha UH, Lim JH, Kim HJ, Wu W, Jin S, Xu H, Li JD Number of Citations: 4 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA to examine the effect of genistein and curcumin on mucin production in human airway epithelial cells Phytother Res. 2009 Oct;23(10):1458-61. "Genistein and curcumin suppress epidermal growth factor-induced MUC5AC mucin production and gene expression from human airway epithelial cells." Author(s): Heo HJ, Lee SY, Lee MN, Lee HJ, Seok JH, Lee CJ Number of Citations: 3 (See PubMed article )
	Hu / 1:16000	MA1-25073 was used in ELISA to study the role of dysfunctional mitochondria in allergic airway inflammation J Immunol. 2009 Oct 15;183(8):5379-87. "Mitochondrial dysfunction increases allergic airway inflammation." Author(s): Aguilera-Aguirre L, Bacsi A, Saavedra-Molina A, Kurosky A, Sur S, Boldogh I Number of Citations: 1 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA to investigate the mechanism of MUC5B upregulation induced by leptin Exp Lung Res. 2010 Jun;36(5):262-9. "Leptin up-regulates MUC5B expression in human airway epithelial cells via mitogen-activated protein kinase pathway." Author(s): Woo HJ, Yoo WJ, Bae CH, Song SY, Kim YW, Park SY, Kim YD Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the effect of aclidinium on MUC5AC expression in airway epithelial cells Eur Respir J. 2011 Feb;37(2):244-54. "Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways." Author(s): Cortijo J, Mata M, Milara J, Donet E, Gavaldà A, Miralpeix M, Morcillo EJ Number of Citations: 1 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA to examine the MUC5AC protein level in the middle ear fluids from otitis media patients Arch Otolaryngol Head Neck Surg. 2010 Aug;136(8):819-24. "MUC5AC expression in human middle ear epithelium of patients with otitis media." Author(s): Kerschner JE, Tripathi S, Khampang P, Papsin BC Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in ELISA and immunocytochemistry to investigate the effect of cigarette smoke on the regulation of inflammation in airway epithelial cells Transl Res. 2010 Dec;156(6):326-34. "Nicotine suppresses inflammatory factors in HBE16 airway epithelial cells after exposure to cigarette smoke extract and lipopolysaccharide." Author(s): Li Q, Zhou X, Kolosov VP, Perelman JM Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA and immunocytochemistry to investigate the changes of gene expression and signal regulation induced by cigarette smoke in human airway epithelial cells J Appl Toxicol. 2012 Apr;32(4):282-92. "Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1? via epidermal growth factor receptor-mediated signaling pathways." Author(s): Yu H, Li Q, Kolosov VP, Perelman JM, Zhou X Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA to study the effect of guaifenesin on mucin production in human airway epithelial cells Exp Lung Res. 2011 Dec;37(10):606-14. "Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells." Author(s): Seagrave J, Albrecht H, Park YS, Rubin B, Solomon G, Kim KC Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA and immunohistochemistry to study the effect of IL-13 on MUC5AC and goblet cell differentiation in human airway cells Clin Exp Allergy. 2011 Dec;41(12):1747-56. "IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells." Author(s): Kanoh S, Tanabe T, Rubin BK Number of Citations: 1 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA to investigate the effect of silibinin on gene expression, production, and secretion of mucin from NCI-H292 cells Phytother Res. 2012 Jan 25;():. "Silibinin Regulates Gene Expression, Production and Secretion of Mucin from Cultured Airway Epithelial Cells." Author(s): Kim KD, Lee HJ, Lim SP, Sikder MA, Lee SY, Lee CJ Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in ELISA to investigate the effect of CD8+ T cells on macrophage accumulation and airspace enlargement following repeated irritant exposure Exp Mol Pathol. 2007 Dec;83(3):301-10. "CD8+ T cells contribute to macrophage accumulation and airspace enlargement following repeated irritant exposure." Author(s): Borchers MT, Wesselkamper SC, Harris NL, Deshmukh H, Beckman E, Vitucci M, Tichelaar JW, Leikauf GD Number of Citations: 1 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in ELISA to examine the role of human neutrophil peptide-1 in mucus hypersecretion during chronic respiratory tract infections J Antimicrob Chemother. 2009 Jan;63(1):109-14. "Different effects of telithromycin on MUC5AC production induced by human neutrophil peptide-1 or lipopolysaccharide in NCI-H292 cells compared with azithromycin and clarithromycin." Author(s): Ishimoto H, Mukae H, Sakamoto N, Amenomori M, Kitazaki T, Imamura Y, Fujita H, Ishii H, Nakayama S, Yanagihara K, Kohno S Number of Citations: 4 (See PubMed article )
	Ms / 2 ug/ml	MA1-25073 was used in ELISA to investigate the effect of roflumilast on lung injury induced by bleomycin Br J Pharmacol. 2009 Feb;156(3):534-44. "Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury." Author(s): Cortijo J, Iranzo A, Milara X, Mata M, Cerdá-Nicolás M, Ruiz-Saurí A, Tenor H, Hatzelmann A, Morcillo EJ Number of Citations: 1 (See PubMed article )
	Ms / 1:500	MA1-25073 was used in ELISA to investigate the regulatory effect of MARCKS-related peptide on airway mucin secretion Am J Physiol Lung Cell Mol Physiol. 2010 Sep;299(3):L345-52. "MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac." Author(s): Foster WM, Adler KB, Crews AL, Potts EN, Fischer BM, Voynow JA Number of Citations: 1 (See PubMed article )
	Ms / 1:200	MA1-25073 was used in ELISA to investigate the protective effect of Nrf2 on pulmonary inflammation induced by influenza virus in mice exposed to cigarette smoke J Virol. 2011 May;85(10):4679-90. "Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice." Author(s): Yageta Y, Ishii Y, Morishima Y, Masuko H, Ano S, Yamadori T, Itoh K, Takeuchi K, Yamamoto M, Hizawa N Number of Citations: 1 (See PubMed article )
	Rt / 1:100	MA1-25073 was used in ELISA and western blot to investigate the influence of N-acetylcysteine on lung injury treatment and Muc5ac gene expression in rats Eur Respir J. 2003 Dec;22(6):900-5. "Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats." Author(s): Mata M, Ruíz A, Cerdá M, Martinez-Losa M, Cortijo J, Santangelo F, Serrano-Mollar A, Llombart-Bosch A, Morcillo EJ Number of Citations: 8 (See PubMed article )
	Rt / 1:200	MA1-25073 was used in ELISA to investigate the influence of dexamethasone on Muc5ac production in primary airway goblet cells Am J Physiol Lung Cell Mol Physiol. 2005 Jan;288(1):L52-60. "Effects of dexamethasone on Muc5ac mucin production by primary airway goblet cells." Author(s): Lu W, Lillehoj EP, Kim KC Number of Citations: 1 (See PubMed article )
	Rt / 1:100	MA1-25073 was used in ELISA to evaluate an assay for the measurement of mucin levels in bronchoalveolar lavage fluid J Pharmacol Toxicol Methods. 2006 Mar-Apr;53(2):160-7. "An enzyme-linked immunosorbent assay (ELISA) for the determination of mucin levels in bronchoalveolar lavage fluid." Author(s): Phillips JE, Case NR, Celly C, Chapman RW, Hey JA, Minnicozzi M Number of Citations: 1 (See PubMed article )

Flow Cytometry
	Species / Dilution	Summary
	Hu / 1:250	MA1-25073 was used in flow cytometry and western blot to investigate the mechanism of MUC5AC stimulation by PGF2alpha J Immunol. 2009 Feb 15;182(4):2349-56. "CREB mediates prostaglandin F2alpha-induced MUC5AC overexpression." Author(s): Chung WC, Ryu SH, Sun H, Zeldin DC, Koo JS Number of Citations: 1 (See PubMed article )
	Hu / 10 ug/ml	MA1-25073 was used in flow cytometry and immunocytochemistry to study the mechanism for the smoke-induced goblet cell hyperplasia Toxicol In Vitro. 2010 Apr;24(3):981-7. "Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: a potential model of goblet cell hyperplasia." Author(s): Haswell LE, Hewitt K, Thorne D, Richter A, Gaça MD Number of Citations: 1 (See PubMed article )

Immunocytochemistry
	Species / Dilution	Summary
	Hm / 1:100	MA1-25073 was used in immunocytochemistry to generate and characterize primary airway epithelial cell cultures from Syrian golden hamsters In Vitro Cell Dev Biol Anim. 2004 Nov-Dec;40(10):303-11. "Differentiated cultures of primary hamster tracheal airway epithelial cells." Author(s): Rowe RK, Brody SL, Pekosz A Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunocytochemistry to investigate production and secretion and of mucin glycoforms in HT29-18N2 cells Am J Physiol. 1999 Jul;277(1 Pt 1):G191-200. "Selective secretion and replenishment of discrete mucin glycoforms from intestinal goblet cells." Author(s): Stanley CM, Phillips TE Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunocytochemistry and western blot to investigate the effect of RAR alpha antagonist on the induction of mucin gene expression Exp Lung Res. 2002 Jun;28(4):315-32. "Overexpression of mucin genes induced by interleukin-1 beta, tumor necrosis factor-alpha, lipopolysaccharide, and neutrophil elastase is inhibited by a retinoic acid receptor alpha antagonist." Author(s): Koo JS, Kim YD, Jetten AM, Belloni P, Nettesheim P Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunocytochemistry to investigate the mechanism by which neutrophil elastase induces mucin production Am J Physiol Lung Cell Mol Physiol. 2002 Sep;283(3):L531-40. "Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation." Author(s): Kohri K, Ueki IF, Nadel JA Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunocytochemistry to investigate the influence of interleukin 13 on human bronchial epithelial cell cultures and its mechanism Am J Physiol Lung Cell Mol Physiol. 2003 Sep;285(3):L730-9. "IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation." Author(s): Atherton HC, Jones G, Danahay H Number of Citations: 1 (See PubMed article )
	Hu / 1:250	MA1-25073 was used in immunocytochemistry to study the effect of IL-1beta on MUC5AC mucin secretion and airway surface liquid metabolism in human bronchial epithelia Am J Physiol Lung Cell Mol Physiol. 2004 Feb;286(2):L320-30. "Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia." Author(s): Gray T, Coakley R, Hirsh A, Thornton D, Kirkham S, Koo JS, Burch L, Boucher R, Nettesheim P Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunocytochemistry to investigate the influence of pH on mucin granule organization in mucous/goblet J Biol Chem. 2005 Apr 29;280(17):16868-81. "pH-dependent intraluminal organization of mucin granules in live human mucous/goblet cells." Author(s): Perez-Vilar J, Olsen JC, Chua M, Boucher RC Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunocytochemistry to investigate the role of E-cadherin in the epidermal growth factor receptor-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1049-60. "E-cadherin promotes EGFR-mediated cell differentiation and MUC5AC mucin expression in cultured human airway epithelial cells." Author(s): Kim S, Schein AJ, Nadel JA Number of Citations: 1 (See PubMed article )
	Hu / Not Cited	MA1-25073 was used in blocking or activating experiment and immunocytochemistry to examine the involvement of coagulation factor Xa in the pathogenesis of asthma Am J Respir Crit Care Med. 2007 Jan 15;175(2):136-43. "Coagulation factor Xa modulates airway remodeling in a murine model of asthma." Author(s): Shinagawa K, Martin JA, Ploplis VA, Castellino FJ Number of Citations: 6 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in immunocytochemistry to investigate the expression of carboxyl-terminal hydrolyase L1 gene in human airway epithelium of cigarette smokers Cancer Res. 2006 Nov 15;66(22):10729-40. "Up-regulation of expression of the ubiquitin carboxyl-terminal hydrolase L1 gene in human airway epithelium of cigarette smokers." Author(s): Carolan BJ, Heguy A, Harvey BG, Leopold PL, Ferris B, Crystal RG Number of Citations: 1 (See PubMed article )
	Hu / 2 ug/ml	MA1-25073 was used in immunocytochemistry to examine the effect of cigarette smoke exposure on gene expression in human bronchial epithelial cells Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1248-56. "Human bronchial epithelial cell transcriptome: gene expression changes following acute exposure to whole cigarette smoke in vitro." Author(s): Maunders H, Patwardhan S, Phillips J, Clack A, Richter A Number of Citations: 10 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunocytochemistry to investigate the role of the interleukin-13 in human airway epithelial cell differentiation Exp Cell Res. 2007 Jul 15;313(12):2695-702. "Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation." Author(s): Skowron-zwarg M, Boland S, Caruso N, Coraux C, Marano F, Tournier F Number of Citations: 1 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA and immunocytochemistry to study the role of the hCLCA1 pathway in the induction of MUC5AC expression by histamine Pharmacology. 2007;80(4):219-26. "Histamine induces MUC5AC expression via a hCLCA1 pathway." Author(s): Kim YM, Won TB, Kim SW, Min YG, Lee CH, Rhee CS Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunocytochemistry to investigate the role of epidermal growth factor receptor in airway goblet cell hyperplasia Clin Exp Allergy. 2008 May;38(5):857-65. "Role of epidermal growth factor receptor in maintaining airway goblet cell hyperplasia in rats sensitized to allergen." Author(s): Takeyama K, Tamaoki J, Kondo M, Isono K, Nagai A Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunocytochemistry to examine the effect of IL-13 on subepithelial fibrosis Respir Res. 2008 Mar 18;9():27. "IL-13 induces a bronchial epithelial phenotype that is profibrotic." Author(s): Malavia NK, Mih JD, Raub CB, Dinh BT, George SC Number of Citations: 3 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunocytochemistry and western blot to investigate the effect of chronic intermittent mechanical stress on expression of MUC5AC in human bronchial epithelial cells Am J Respir Cell Mol Biol. 2009 Oct;41(4):459-66. "Chronic intermittent mechanical stress increases MUC5AC protein expression." Author(s): Park JA, Tschumperlin DJ Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunocytochemistry to investigate the role of Duox NADPH oxidase heterodimerization in its localization in airway cells J Cell Sci. 2009 Apr 15;122(Pt 8):1238-47. "Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells." Author(s): Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in flow cytometry and immunocytochemistry to study the mechanism for the smoke-induced goblet cell hyperplasia Toxicol In Vitro. 2010 Apr;24(3):981-7. "Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: a potential model of goblet cell hyperplasia." Author(s): Haswell LE, Hewitt K, Thorne D, Richter A, Gaça MD Number of Citations: 1 (See PubMed article )
	Hu / 1:200	MA1-25073 was used in ELISA and immunocytochemistry to investigate the effect of cigarette smoke on the regulation of inflammation in airway epithelial cells Transl Res. 2010 Dec;156(6):326-34. "Nicotine suppresses inflammatory factors in HBE16 airway epithelial cells after exposure to cigarette smoke extract and lipopolysaccharide." Author(s): Li Q, Zhou X, Kolosov VP, Perelman JM Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA and immunocytochemistry to investigate the changes of gene expression and signal regulation induced by cigarette smoke in human airway epithelial cells J Appl Toxicol. 2012 Apr;32(4):282-92. "Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1? via epidermal growth factor receptor-mediated signaling pathways." Author(s): Yu H, Li Q, Kolosov VP, Perelman JM, Zhou X Number of Citations: 1 (See PubMed article )
	Hu / 1:50	MA1-25073 was used in immunocytochemistry to investigate the effect of cigarette smoke on GDF15 expression in human lung epithelial cells Innate Immun. 2012;18(4):617-26. "Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: Implication in mucin over-expression." Author(s): Wu Q, Jiang D, Chu HW Number of Citations: 1 (See PubMed article )
	Rt / Not Cited	MA1-25073 was used in immunocytochemistry to investigate the application of new culture substratum in airway tissue reconstitution in vitro Connect Tissue Res. 2007;48(1):9-18. "Differentiation of tracheal basal cells to ciliated cells and tissue reconstruction on the synthesized basement membrane substratum in vitro." Author(s): Hosokawa T, Betsuyaku T, Nishimura M, Furuyama A, Katagiri K, Mochitate K Number of Citations: 1 (See PubMed article )

Immunohistochemistry
	Species / Dilution	Summary
	Av / 1:100	MA1-25073 was used in immunohistochemistry to investigate the MUC5AC expression in the oesophageal mucosa of quail post-hatching Anat Histol Embryol. 2009 Oct;38(5):330-40. "Structure of the oesophagus and morphometric, histochemical-immunohistochemical profiles of the oesophageal gland during the post-hatching period of Japanese quails (Coturnix coturnix japonica)." Author(s): Sa?söz H, Liman N Number of Citations: 1 (See PubMed article )
	Ca / 1:300	MA1-25073 was used in immunohistochemistry, immunohistochemistry, and immunohistochemistry to investigate the influenza virus receptor specificity and cell-specific expression in mouse and human airway epithelial cells J Virol. 2006 Aug;80(15):7469-80. "Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells." Author(s): Ibricevic A, Pekosz A, Walter MJ, Newby C, Battaile JT, Brown EG, Holtzman MJ, Brody SL Number of Citations: 1 (See PubMed article )
	GP / 1:100	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the differential expression and secretion of Muc2 and Muc5ac in guinea pig tracheal epithelial cells Respir Res. 2006 Feb 25;7():35. "Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro." Author(s): Chorley BN, Crews AL, Li Y, Adler KB, Minnicozzi M, Martin LD Number of Citations: 1 (See PubMed article )
	GP / 1:50	MA1-25073 was used in immunohistochemistry to investigate the regulatory effect of Munc18/SNARE proteins on exocytosis in Brunner gland acini World J Gastroenterol. 2008 Apr 21;14(15):2314-22. "Munc18/SNARE proteins' regulation of exocytosis in guinea pig duodenal Brunner's gland acini." Author(s): Cosen-Binker LI, Morris GP, Vanner S, Gaisano HY Number of Citations: 2 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry to investigate the expression of calcium-activated chloride channel 1 in the asthmatic airway and its role in asthmatic pathogenesis Am J Respir Crit Care Med. 2002 Apr 15;165(8):1132-6. "Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway." Author(s): Hoshino M, Morita S, Iwashita H, Sagiya Y, Nagi T, Nakanishi A, Ashida Y, Nishimura O, Fujisawa Y, Fujino M Number of Citations: 12 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to investigate the expression of MUC1 and MUC3 in gastric carcinoma J Clin Pathol. 2003 May;56(5):378-84. "Alterations of MUC1 and MUC3 expression in gastric carcinoma: relevance to patient clinicopathological features." Author(s): Wang RQ, Fang DC Number of Citations: 4 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to study the prognostic significance of MUC1 and MUC5AC expression in gastric cancer J Surg Oncol. 2003 Aug;83(4):253-60. "Role of MUC1 and MUC5AC expressions as prognostic indicators in gastric carcinomas." Author(s): Wang JY, Chang CT, Hsieh JS, Lee LW, Huang TJ, Chai CY, Lin SR Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to study the prognostic value of MUC5AC expression in adenocarcinomas of the uterine cervix Ann Surg Oncol. 2004 Jan;11(1):40-4. "Correlation between MUC5AC expression and the prognosis of patients with adenocarcinoma of the uterine cervix." Author(s): Mitsuhashi A, Yamazawa K, Nagai Y, Tanaka N, Matsui H, Sekiya S Number of Citations: 0 (See PubMed article )
	Hu / Not Cited	MA1-25073 was used in immunohistochemistry to report the clinicopathologic and immunohistochemical features of primary mucinous carcinomas of the lung Am J Surg Pathol. 2004 Apr;28(4):442-52. "Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression." Author(s): Rossi G, Murer B, Cavazza A, Losi L, Natali P, Marchioni A, Migaldi M, Capitanio G, Brambilla E Number of Citations: 2 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry to study the association of MUC5AC with altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas Pathol Res Pract. 2004;200(5):371-7. "Relationship between MUC5AC and altered expression of MLH1 protein in mucinous and non-mucinous colorectal carcinomas." Author(s): Losi L, Scarselli A, Benatti P, Ponz de Leon M, Roncucci L, Pedroni M, Borghi F, Lamberti I, Rossi G, Marino M, Ponti G, Zangardi G, Menigatti M, Di Gregorio C Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry and western blot to study the mechanism for the effect of interleukin 1 beta on mucin production in human airway epithelium Mol Pharmacol. 2004 Aug;66(2):337-46. "Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling." Author(s): Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunohistochemistry to investigate the influence of intranasal steroids on specific gene expression in nasal polyps Eur Respir J. 2004 Oct;24(4):594-600. "Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps." Author(s): Burgel PR, Cardell LO, Ueki IF, Nadel JA Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the influence of PDE4 inhibition on mucin expression in human airway epithelial cells Thorax. 2005 Feb;60(2):144-52. "Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells." Author(s): Mata M, Sarriá B, Buenestado A, Cortijo J, Cerdá M, Morcillo EJ Number of Citations: 10 (See PubMed article )
	Hu / 1:1000	MA1-25073 was used in immunohistochemistry to study the involvement of MUC5B gene in diffuse panbronchiolitis Am J Respir Crit Care Med. 2005 May 1;171(9):949-57. "Promoter analysis and aberrant expression of the MUC5B gene in diffuse panbronchiolitis." Author(s): Kamio K, Matsushita I, Hijikata M, Kobashi Y, Tanaka G, Nakata K, Ishida T, Tokunaga K, Taguchi Y, Homma S, Nakata K, Azuma A, Kudoh S, Keicho N Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to investigate the gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach Histopathology. 2005 May;46(5):505-14. "Tissue microarray analysis of multiple gene expression in intestinal metaplasia, dysplasia and carcinoma of the stomach." Author(s): Sun Y, Li JY, He JS, Zhou LX, Chen K Number of Citations: 1 (See PubMed article )
	Hu / Not Cited	MA1-25073 was used in immunohistochemistry to investigate the characteristics of gastric, indefinite, and reactive hyperplasia World J Gastroenterol. 2005 Jun 21;11(23):3595-600. "Differences in biological features of gastric dysplasia, indefinite dysplasia, reactive hyperplasia and discriminant analysis of these lesions." Author(s): Dong B, Xie YQ, Chen K, Wang T, Tang W, You WC, Li JY Number of Citations: 0 (See PubMed article )
	Hu / 1:300	MA1-25073 was used in immunohistochemistry to investigate the role of suplatast tosilate in goblet cell metaplasia in patients with asthma Allergy. 2005 Nov;60(11):1394-400. "Effect of suplatast tosilate on goblet cell metaplasia in patients with asthma." Author(s): Hoshino M, Fujita Y, Saji J, Inoue T, Nakagawa T, Miyazawa T Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry to study the therapeutic appraches for inhibiting airway mucous cell metaplasia J Clin Invest. 2006 Feb;116(2):309-21. "Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals." Author(s): Tyner JW, Kim EY, Ide K, Pelletier MR, Roswit WT, Morton JD, Battaile JT, Patel AC, Patterson GA, Castro M, Spoor MS, You Y, Brody SL, Holtzman MJ Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to study the role of Helicobacter pylori infection on the pathogenesis of gastric carcinoma J Gastroenterol Hepatol. 2006 Feb;21(2):425-31. "Effects of Helicobacter pylori infection on mucin expression in gastric carcinoma and pericancerous tissues." Author(s): Wang RQ, Fang DC Number of Citations: 1 (See PubMed article )
	Hu / 1:300	MA1-25073 was used in immunohistochemistry, immunohistochemistry, and immunohistochemistry to investigate the influenza virus receptor specificity and cell-specific expression in mouse and human airway epithelial cells J Virol. 2006 Aug;80(15):7469-80. "Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells." Author(s): Ibricevic A, Pekosz A, Walter MJ, Newby C, Battaile JT, Brown EG, Holtzman MJ, Brody SL Number of Citations: 1 (See PubMed article )
	Hu / 1:1000	MA1-25073 was used in immunohistochemistry to investigate the changes of mucous cells in cystic fibrosis Am J Respir Crit Care Med. 2006 Nov 1;174(9):1018-24. "Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils." Author(s): Hays SR, Fahy JV Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunohistochemistry to investigate the changes of small airway plugging and mucin expression in cystic fibrosis Thorax. 2007 Feb;62(2):153-61. "A morphometric study of mucins and small airway plugging in cystic fibrosis." Author(s): Burgel PR, Montani D, Danel C, Dusser DJ, Nadel JA Number of Citations: 1 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in ELISA and immunohistochemistry to investigate the overproduction of MUC5AC in gallstone disease and its mechanism Am J Pathol. 2006 Dec;169(6):2031-41. "MUC5AC, a gel-forming mucin accumulating in gallstone disease, is overproduced via an epidermal growth factor receptor pathway in the human gallbladder." Author(s): Finzi L, Barbu V, Burgel PR, Mergey M, Kirkwood KS, Wick EC, Scoazec JY, Peschaud F, Paye F, Nadel JA, Housset C Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to investigate the expression profiles of mucins in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas Int J Cancer. 2007 Dec 15;121(12):2716-22. "Diagnostic value of mucins (MUC1, MUC2 and MUC5AC) expression profile in endoscopic ultrasound-guided fine-needle aspiration specimens of the pancreas." Author(s): Wang Y, Gao J, Li Z, Jin Z, Gong Y, Man X Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to investigate the mechanism for upregulation of MUC5AC mucin expression induced by Pseudomonas aeruginosa lipopolysaccharide in human airway epithelial cells Biochem Biophys Res Commun. 2008 Feb 8;366(2):513-9. "Reactive oxygen species regulate Pseudomonas aeruginosa lipopolysaccharide-induced MUC5AC mucin expression via PKC-NADPH oxidase-ROS-TGF-alpha signaling pathways in human airway epithelial cells." Author(s): Yan F, Li W, Jono H, Li Q, Zhang S, Li JD, Shen H Number of Citations: 1 (See PubMed article )
	Hu / 1:2000	MA1-25073 was used in immunohistochemistry to investigate phenotypic mucin expression in human gastric adenocarcinoma J Gastroenterol Hepatol. 2009 Apr;24(4):658-66. "Unclassified mucin phenotype of gastric adenocarcinoma exhibits the highest invasiveness." Author(s): Han HS, Lee SY, Lee KY, Hong SN, Kim JH, Sung IK, Park HS, Jin CJ, Min YI Number of Citations: 0 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry to develop a combined clinicopathologic and molecular scoring system for assessing the tumor responses to EGFR inhibitors Am J Clin Pathol. 2009 Apr;131(4):478-89. "EGFR and K-ras mutations along the spectrum of pulmonary epithelial tumors of the lung and elaboration of a combined clinicopathologic and molecular scoring system to predict clinical responsiveness to EGFR inhibitors." Author(s): Sartori G, Cavazza A, Sgambato A, Marchioni A, Barbieri F, Longo L, Bavieri M, Murer B, Meschiari E, Tamberi S, Cadioli A, Luppi F, Migaldi M, Rossi G Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry to characterize the expression of a number of proteins in tissues from pseudomyxoma peritonei patients Hum Pathol. 2010 Aug;41(8):1109-19. "Exploring the peritoneal surface malignancy phenotype--a pilot immunohistochemical study of human pseudomyxoma peritonei and derived animal models." Author(s): Flatmark K, Davidson B, Kristian A, Stavnes HT, Førsund M, Reed W Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the effect of aclidinium on MUC5AC expression in airway epithelial cells Eur Respir J. 2011 Feb;37(2):244-54. "Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways." Author(s): Cortijo J, Mata M, Milara J, Donet E, Gavaldà A, Miralpeix M, Morcillo EJ Number of Citations: 1 (See PubMed article )
	Hu / 1:100	MA1-25073 was used in immunohistochemistry and immunohistochemistry to evaluate an appendiceal mucinous adenocarcinoma model Int J Exp Pathol. 2010 Aug;91(4):357-67. "Establishment and characterization of a murine xenograft model of appendiceal mucinous adenocarcinoma." Author(s): Mavanur AA, Parimi V, O'Malley M, Nikiforova M, Bartlett DL, Davison JM Number of Citations: 1 (See PubMed article )
	Hu / 2 ug/mL	MA1-25073 was used in immunohistochemistry to investigate the role of DUOX2 in inflammation mediated by TLR5 in airway mucosa Antioxid Redox Signal. 2012 Jan 1;16(1):57-70. "Dual oxidase 2 is essential for the toll-like receptor 5-mediated inflammatory response in airway mucosa." Author(s): Joo JH, Ryu JH, Kim CH, Kim HJ, Suh MS, Kim JO, Chung SY, Lee SN, Kim HM, Bae YS, Yoon JH Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA and immunohistochemistry to study the effect of IL-13 on MUC5AC and goblet cell differentiation in human airway cells Clin Exp Allergy. 2011 Dec;41(12):1747-56. "IL-13-induced MUC5AC production and goblet cell differentiation is steroid resistant in human airway cells." Author(s): Kanoh S, Tanabe T, Rubin BK Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry to study the role of acetylcholine and nicotinic receptors in mucus cell pathophysiology and airway mucus formation J Allergy Clin Immunol. 2012 Sep;130(3):770-780.e11. "Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo." Author(s): Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Peña-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML Number of Citations: 0 (See PubMed article )
	Ms / 2 ug/ml	MA1-25073 was used in immunohistochemistry to characterize the a chronic asthma phenotype induced by paramyxoviruses J Clin Invest. 2002 Jul;110(2):165-75. "Viral induction of a chronic asthma phenotype and genetic segregation from the acute response." Author(s): Walter MJ, Morton JD, Kajiwara N, Agapov E, Holtzman MJ Number of Citations: 1 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in immunohistochemistry to evaluate an invivo mouse model for the study of recurrent corneal epithelial erosions Invest Ophthalmol Vis Sci. 2004 Jun;45(6):1775-88. "A mouse model for the study of recurrent corneal epithelial erosions: alpha9beta1 integrin implicated in progression of the disease." Author(s): Pal-Ghosh S, Pajoohesh-Ganji A, Brown M, Stepp MA Number of Citations: 10 (See PubMed article )
	Ms / 2 ug/ml	MA1-25073 was used in immunohistochemistry to identify the genes involved in the complex airway disease traits Physiol Genomics. 2006 May 16;25(3):502-13. "Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members." Author(s): Patel AC, Morton JD, Kim EY, Alevy Y, Swanson S, Tucker J, Huang G, Agapov E, Phillips TE, Fuentes ME, Iglesias A, Aud D, Allard JD, Dabbagh K, Peltz G, Holtzman MJ Number of Citations: 1 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in immunohistochemistry to examine the differentiation potential of immortalized human bronchial epithelial cells Differentiation. 2006 Apr;74(4):141-8. "A three-dimensional model of differentiation of immortalized human bronchial epithelial cells." Author(s): Vaughan MB, Ramirez RD, Wright WE, Minna JD, Shay JW Number of Citations: 17 (See PubMed article )
	Ms / 1:300	MA1-25073 was used in immunohistochemistry, immunohistochemistry, and immunohistochemistry to investigate the influenza virus receptor specificity and cell-specific expression in mouse and human airway epithelial cells J Virol. 2006 Aug;80(15):7469-80. "Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells." Author(s): Ibricevic A, Pekosz A, Walter MJ, Newby C, Battaile JT, Brown EG, Holtzman MJ, Brody SL Number of Citations: 1 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in immunohistochemistry to investigate the influence of Sox2 dosage on anterior foregut endoderm development Development. 2007 Jul;134(13):2521-31. "Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm." Author(s): Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in immunohistochemistry to investigate the role of a GABAergic system in airway epithelium in mucus overproduction in asthma Nat Med. 2007 Jul;13(7):862-7. "A GABAergic system in airway epithelium is essential for mucus overproduction in asthma." Author(s): Xiang YY, Wang S, Liu M, Hirota JA, Li J, Ju W, Fan Y, Kelly MM, Ye B, Orser B, O'Byrne PM, Inman MD, Yang X, Lu WY Number of Citations: 1 (See PubMed article )
	Ms / 1:200	MA1-25073 was used in immunohistochemistry to investigate the role of A2A adenosine receptor in pulmonary inflammation and angiogenesis Am J Physiol Lung Cell Mol Physiol. 2007 Sep;293(3):L753-61. "Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice." Author(s): Mohsenin A, Mi T, Xia Y, Kellems RE, Chen JF, Blackburn MR Number of Citations: 1 (See PubMed article )
	Ms / 1:300	MA1-25073 was used in immunohistochemistry to investigate the fate of airway epithelial cells after allogeneic orthotopic lung transplantation Am J Respir Cell Mol Biol. 2007 Dec;37(6):625-30. "Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants." Author(s): Okazaki M, Gelman AE, Tietjens JR, Ibricevic A, Kornfeld CG, Huang HJ, Richardson SB, Lai J, Garbow JR, Patterson GA, Krupnick AS, Brody SL, Kreisel D Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in immunohistochemistry to investigate the markers for functional multipotent adult stem cells from mammalian testicles Nature. 2007 Sep 20;449(7160):346-50. "Generation of functional multipotent adult stem cells from GPR125+ germline progenitors." Author(s): Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in immunohistochemistry to characterize a CD34+ testicular stromal cell line as a feeder cell line for embryonic and adult stem and progenitor cells Stem Cells. 2008 Oct;26(10):2516-22. "CD34+ testicular stromal cells support long-term expansion of embryonic and adult stem and progenitor cells." Author(s): Kim J, Seandel M, Falciatori I, Wen D, Rafii S Number of Citations: 1 (See PubMed article )
	Ms / 1:100	MA1-25073 was used in immunohistochemistry and western blot to investigate the mechanism for the effect of glycyrrhizin on mucus production J Pharmacol Sci. 2010;113(1):76-83. "Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro." Author(s): Nishimoto Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y Number of Citations: 0 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in immunohistochemistry to study the involvement of the aquaporin 5 water channel in chronic allergic asthma J Cell Mol Med. 2011 Jun;15(6):1355-63. "Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice." Author(s): Shen Y, Wang Y, Chen Z, Wang D, Wang X, Jin M, Bai C Number of Citations: 1 (See PubMed article )
	Ms / 1:25	MA1-25073 was used in immunohistochemistry and immunohistochemistry to evaluate an appendiceal mucinous adenocarcinoma model Int J Exp Pathol. 2010 Aug;91(4):357-67. "Establishment and characterization of a murine xenograft model of appendiceal mucinous adenocarcinoma." Author(s): Mavanur AA, Parimi V, O'Malley M, Nikiforova M, Bartlett DL, Davison JM Number of Citations: 1 (See PubMed article )
	Ms / 1:200	MA1-25073 was used in immunohistochemistry to study the roles of SLURP-1 in the pathophysiology of asthma. Biochem Biophys Res Commun. 2010 Aug 6;398(4):713-8. "Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric alpha7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions." Author(s): Narumoto O, Horiguchi K, Horiguchi S, Moriwaki Y, Takano-Ohmuro H, Shoji S, Misawa H, Yamashita N, Nagase T, Kawashima K, Yamashita N Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in immunohistochemistry to investigate the role of calpain 8/nCL-2 and calpain 9/nCL-4 in gastric mucosal defense PLoS Genet. 2010 Jul 29;6(7):e1001040. "Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense." Author(s): Hata S, Abe M, Suzuki H, Kitamura F, Toyama-Sorimachi N, Abe K, Sakimura K, Sorimachi H Number of Citations: 1 (See PubMed article )
	Po / 1:50	MA1-25073 was used in immunohistochemistry to investigate the stem cell potential of primitive germ cells isolated from neonatal pig testis Reprod Fertil Dev. 2009;21(5):696-708. "Multipotential ability of primitive germ cells from neonatal pig testis cultured in vitro." Author(s): Goel S, Fujihara M, Tsuchiya K, Takagi Y, Minami N, Yamada M, Imai H Number of Citations: 1 (See PubMed article )
	Rt / 2 ug/ml	MA1-25073 was used in immunohistochemistry to evaluate a novel fixation method for lung tissue J Immunol Methods. 2001 Jan 1;247(1-2):187-90. "Ethanol vapour-fixation of rat lung for immunocytochemistry investigations." Author(s): Wilson HH, Chauhan J, Kerry PJ, Evans JG Number of Citations: 2 (See PubMed article )
	Rt / 1:200	MA1-25073 was used in immunohistochemistry to investigate the influence of S-carboxymethylcysteine on airway inflammation, mucus cells and MUC5AC expression in a rat model Int Arch Allergy Immunol. 2004 Aug;134(4):273-80. "Reduced airway inflammation and remodeling in parallel with mucin 5AC protein expression decreased by s-carboxymethylcysteine, a mucoregulant, in the airways of rats exposed to sulfur dioxide." Author(s): Sueyoshi S, Miyata Y, Masumoto Y, Ishibashi Y, Matsuzawa S, Harano N, Tsuru K, Imai S Number of Citations: 1 (See PubMed article )

Immunoprecipitation
	Species / Dilution	Summary
	Rt / 1:200	MA1-25073 was used in immunoprecipitation to examine the mechanism for the effect of sulfur dioxide on the airway of asthmatic rats Regul Toxicol Pharmacol. 2007 Aug;48(3):284-91. "Effects of sulfur dioxide on the expressions of MUC5AC and ICAM-1 in airway of asthmatic rats." Author(s): Li R, Meng Z, Xie J Number of Citations: 0 (See PubMed article )

Western Blot
	Species / Dilution	Summary
	GP / 0	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the differential expression and secretion of Muc2 and Muc5ac in guinea pig tracheal epithelial cells Respir Res. 2006 Feb 25;7():35. "Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro." Author(s): Chorley BN, Crews AL, Li Y, Adler KB, Minnicozzi M, Martin LD Number of Citations: 1 (See PubMed article )
	Hu / 1:250	MA1-25073 was used in immunocytochemistry and western blot to investigate the effect of RAR alpha antagonist on the induction of mucin gene expression Exp Lung Res. 2002 Jun;28(4):315-32. "Overexpression of mucin genes induced by interleukin-1 beta, tumor necrosis factor-alpha, lipopolysaccharide, and neutrophil elastase is inhibited by a retinoic acid receptor alpha antagonist." Author(s): Koo JS, Kim YD, Jetten AM, Belloni P, Nettesheim P Number of Citations: 1 (See PubMed article )
	Hu / 1:250	MA1-25073 was used in immunohistochemistry and western blot to study the mechanism for the effect of interleukin 1 beta on mucin production in human airway epithelium Mol Pharmacol. 2004 Aug;66(2):337-46. "Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling." Author(s): Gray T, Nettesheim P, Loftin C, Koo JS, Bonner J, Peddada S, Langenbach R Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in western blot to investigate the influence of tumor growth factor beta 2 on mucin expression in asthma Am J Pathol. 2004 Oct;165(4):1097-106. "Transforming growth factor-beta2 induces bronchial epithelial mucin expression in asthma." Author(s): Chu HW, Balzar S, Seedorf GJ, Westcott JY, Trudeau JB, Silkoff P, Wenzel SE Number of Citations: 14 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the influence of PDE4 inhibition on mucin expression in human airway epithelial cells Thorax. 2005 Feb;60(2):144-52. "Phosphodiesterase 4 inhibition decreases MUC5AC expression induced by epidermal growth factor in human airway epithelial cells." Author(s): Mata M, Sarriá B, Buenestado A, Cortijo J, Cerdá M, Morcillo EJ Number of Citations: 10 (See PubMed article )
	Hu / 1:500	MA1-25073 was used in immunocytochemistry and western blot to investigate the effect of chronic intermittent mechanical stress on expression of MUC5AC in human bronchial epithelial cells Am J Respir Cell Mol Biol. 2009 Oct;41(4):459-66. "Chronic intermittent mechanical stress increases MUC5AC protein expression." Author(s): Park JA, Tschumperlin DJ Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in flow cytometry and western blot to investigate the mechanism of MUC5AC stimulation by PGF2alpha J Immunol. 2009 Feb 15;182(4):2349-56. "CREB mediates prostaglandin F2alpha-induced MUC5AC overexpression." Author(s): Chung WC, Ryu SH, Sun H, Zeldin DC, Koo JS Number of Citations: 1 (See PubMed article )
	Hu / 0	MA1-25073 was used in immunohistochemistry and western blot to investigate the mechanism for the effect of glycyrrhizin on mucus production J Pharmacol Sci. 2010;113(1):76-83. "Glycyrrhizin attenuates mucus production by inhibition of MUC5AC mRNA expression in vivo and in vitro." Author(s): Nishimoto Y, Hisatsune A, Katsuki H, Miyata T, Yokomizo K, Isohama Y Number of Citations: 0 (See PubMed article )
	Hu / 0	MA1-25073 was used in ELISA, immunohistochemistry, and western blot to investigate the effect of aclidinium on MUC5AC expression in airway epithelial cells Eur Respir J. 2011 Feb;37(2):244-54. "Aclidinium inhibits cholinergic and tobacco smoke-induced MUC5AC in human airways." Author(s): Cortijo J, Mata M, Milara J, Donet E, Gavaldà A, Miralpeix M, Morcillo EJ Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in western blot to investigate the effect of interleukin 10 expression on mucus production, inflammatory response, and airway integrity J Biol Chem. 2002 Sep 20;277(38):35466-74. "Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways." Author(s): Lee CG, Homer RJ, Cohn L, Link H, Jung S, Craft JE, Graham BS, Johnson TR, Elias JA Number of Citations: 1 (See PubMed article )
	Ms / 0	MA1-25073 was used in western blot to study the role of adenosine in the effect of interleukin 13 in inflammation and remodeling in lungs J Clin Invest. 2003 Aug;112(3):332-44. "Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway." Author(s): Blackburn MR, Lee CG, Young HW, Zhu Z, Chunn JL, Kang MJ, Banerjee SK, Elias JA Number of Citations: 1 (See PubMed article )
	Ms / 1:250	MA1-25073 was used in western blot to study the effect of retinoic acid and Th2 cytokines on mucin glycosylation in a human airway epithelial cell line Am J Physiol Lung Cell Mol Physiol. 2005 Jan;288(1):L116-24. "Mucin biosynthesis: upregulation of core 2 beta 1,6 N-acetylglucosaminyltransferase by retinoic acid and Th2 cytokines in a human airway epithelial cell line." Author(s): Beum PV, Basma H, Bastola DR, Cheng PW Number of Citations: 3 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in western blot to examine the regulatory role of TLR2 signaling in murine mucin production after Mycoplasma pneumoniae infection Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1064-72. "A deficient TLR2 signaling promotes airway mucin production in Mycoplasma pneumoniae-infected allergic mice." Author(s): Wu Q, Martin RJ, Rino JG, Jeyaseelan S, Breed R, Chu HW Number of Citations: 12 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in western blot to examine the role of IL-11 signaling in inflammation and mucus production Am J Respir Cell Mol Biol. 2008 Dec;39(6):739-46. "Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production." Author(s): Lee CG, Hartl D, Matsuura H, Dunlop FM, Scotney PD, Fabri LJ, Nash AD, Chen NY, Tang CY, Chen Q, Homer RJ, Baca M, Elias JA Number of Citations: 7 (See PubMed article )
	Ms / Not Cited	MA1-25073 was used in western blot to study the role of type 1 interferons in the inhibition of VEGF tissue responses by RIG-like helicase innate immunity Am J Respir Crit Care Med. 2011 May 15;183(10):1322-35. "RIG-like helicase innate immunity inhibits vascular endothelial growth factor tissue responses via a type I IFN-dependent mechanism." Author(s): Ma B, Dela Cruz CS, Hartl D, Kang MJ, Takyar S, Homer RJ, Lee CG, Elias JA Number of Citations: 1 (See PubMed article )
	Rt / 1:500	MA1-25073 was used in ELISA and western blot to investigate the influence of N-acetylcysteine on lung injury treatment and Muc5ac gene expression in rats Eur Respir J. 2003 Dec;22(6):900-5. "Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats." Author(s): Mata M, Ruíz A, Cerdá M, Martinez-Losa M, Cortijo J, Santangelo F, Serrano-Mollar A, Llombart-Bosch A, Morcillo EJ Number of Citations: 8 (See PubMed article )

• Products
  • Product Search
  • Cell Biology
  • Cell Signalling
  • Disease
  • Muscle Biology
  • Neurobiology
  • Stem Cell Biology
  • Controls, Secondaries & Tags
  • ELISA Kits
  • Products by Species
  • Products by Catalog Number
  • Products by Name (alphabetical)
  • Antibody Promotions
• Custom Antibodies
  • Antibody Services
    • Custom Antibody Production Services
    • Options for Custom Antibody Production
    • Monospecific Antibody Production Services
    • Assay Validation Options for Custom Antibody Production
    • Quote Form for Custom Antibody Production
  • Antigen Preparation
    • Antigen Profiler Custom Peptide Design System
    • Peptide Synthesis Service for Custom Antibody Production
    • Peptide Conjugation for Custom Antibody Production
    • Protein Expression Services for Custom Antibody Production
  • Monoclonal Antibodies
    • Monoclonal Custom Antibody Development Services
    • Custom Mouse Monoclonal Antibody Development Protocols
    • Custom Rat Monoclonal Antibody Development Protocols
    • Standard ELISA Testing for Monoclonal Antibody Development
    • Screening Options for Monoclonal Antibody Development
    • Monoclonal Antibody Production and Purification Services
  • Polyclonal Antibodies
    • Polyclonal Custom Antibody Development Services
    • Custom Rabbit Custom Antibody Production Protocols
    • Custom Chicken Antibody Production Protocols
    • Custom Goat Antibody Production Protocols
    • Custom Guinea Pig Antibody Production Protocols
    • Custom Mouse Antibody Production Protocols
    • Custom Rat Antibody Production Protocols
    • Purification Options for Custom Polyclonal Antibodies
  • OpenProject
    • OpenProject Online Antibody Production Tool
    • OpenProject Web Tool Help
    • Login to OpenProject
  • Open Bio Customers
  • Request a Quote
• Secondary Antibodies
  • Secondary Antibody Overview
  • Isotype Controls
  • DyLight Fluor Secondary Antibodies
  • Anti-Bovine Secondary Antibodies
  • Anti-Canine Secondary Antibodies
  • Anti-Chicken Secondary Antibodies
  • Anti-Donkey Secondary Antibodies
  • Anti-Feline Secondary Antibodies
  • Anti-Goat Secondary Antibodies
  • Anti-Guinea Pig Secondary Antibodies
  • Anti-Hamster Secondary Antibodies
  • Anti-Human Secondary Antibodies
  • Anti-Horse Secondary Antibodies
  • Anti-Monkey Secondary Antibodies
  • Anti-Mouse Secondary Antibodies
  • Anti-Rabbit Secondary Antibodies
  • Anti-Rat Secondary Antibodies
  • Anti-Sheep Secondary Antibodies
  • Anti-Pig Secondary Antibodies
• Control Antibodies
  • Epitope Tag Antibodies
  • Loading Control Antibodies
• Technical Resources
  • FAQ
  • Protocols
  • Antibody Validation
  • Innovators Program
• About Us
  • Thermo Fisher Scientific
  • Investor Relations
  • Career Opportunities
• Contact Us
  • Technical Support
  • US Customer Service
  • Large Volume & Custom Products
  • International Sales Offices