GJB6 Antibody

GJB6 Polyclonal Antibody for Western blot, IHC

Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu )
Immunogen: Synthetic peptide from the N-terminal region of GJB6 conjugated to KLH.
Ordering Information
Pierce GJB6 Antibody
Product #
PA5-11640
Size
400 ul
Price
$316.00
Purchase
Add GJB6 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:100-1:500
Immunohistochemistry (IHC) 1:50-1:100
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: Lot-specific
Purification: Protein G
Storage Buffer: PBS
Preservative: 0.09% sodium azide
Storage Conditions: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Specific Information
PA5-11640 targets GJB6 in WB and IHC applications and shows reactivity with Human samples. The PA5-11640 immunogen is a synthetic peptide from the N-terminal region of GJB6 conjugated to KLH. PA5-11640 detects GJB6 which has a predicted molecular weight of approximately 30 kDa.
General Information
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
Product Images
  • GJB6 Antibody (PA5-11640) in WB
    GJB6_Antibody_PA5-11640_WB_1_112013.jpg

    Western Blot with anti-GJB6 Polyclonal Antibody (PA5-11640) (GJB6_Antibody_PA5-11640_WB_1_112013.jpg)

    Western Blot with anti-GJB6 Polyclonal Antibody (PA5-11640)

    Western blot analysis of GJB6 (arrow) using anti-GJB6 Polyclonal Antibody (PA5-11640). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GJB6gene (Lane 2).
  • GJB6 Antibody (PA5-11640) in IHC
    GJB6_Antibody_PA5-11640_IHC_1_112013.jpg

    Immunohistochemistry with anti-GJB6 Polyclonal Antibody (PA5-11640) (GJB6_Antibody_PA5-11640_IHC_1_112013.jpg)

    Immunohistochemistry with anti-GJB6 Polyclonal Antibody (PA5-11640)

    Immunohistochemical staining of formalin-fixed and paraffin-embedded human cancer tissue reacted with the anti-GJB6 Polyclonal Antibody (PA5-11640), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
  • GJB6 Antibody (PA5-11640) in IHC
    GJB6_Antibody_PA5-11640_IHC_2_112013.jpg

    Immunohistochemistry with anti-GJB6 Polyclonal Antibody (PA5-11640) (GJB6_Antibody_PA5-11640_IHC_2_112013.jpg)

    Immunohistochemistry with anti-GJB6 Polyclonal Antibody (PA5-11640)

    Immunohistochemical staining of formalin-fixed and paraffin-embedded human prostata carcinoma tissue using anti-GJB6 Polyclonal Antibody (PA5-11640), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific