FUS Antibody

FUS Polyclonal Antibody for Western blot, IF, ICC, IHC (P)

>> See 2 other antibodies for FUS (ALS6, FUS1, HNRNPP2, POMP75, TLS, 75 kDa DNA-pairing protein, RNA-binding protein FUS, fus-like protein, fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, oncogene FUS, oncogene TLS, translocated in liposarcoma protein)
Synonyms:
ALS6, FUS1, HNRNPP2, POMP75, TLS, 75 kDa DNA-pairing protein, RNA-binding protein FUS, fus-like protein, fusion gene in myxoid liposarcoma, heterogeneous nuclear ribonucleoprotein P2, oncogene FUS, oncogene TLS, translocated in liposarcoma protein
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu)
Immunogen: A synthetic peptide made to an N-terminal region of the human FUS protein (within residues 1-150).
Ordering Information
Pierce FUS Antibody
Product #
PA5-23073
Size
100 ul
Price
$316.00
Purchase
Add FUS Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:5000
Immunofluorescence (IF) 1:150
Immunocytochemistry (ICC) 1:150
Immunohistochemistry (Paraffin) (IHC (P)) 1:250
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 1.3mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS with 0.1% BSA, 30% glycerol
Preservative: 0.05% sodium azide
Storage Conditions: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
The target sequence has 95% sequence homology with mouse and 91% sequence homology with bovine.
General Information
The protein originally described as fused in Sarcoma is actually related to a number of different cellular processes and correlated to several diseases. FUS binds DNA as a single or double strand, and acts as a site for transcription factors to recognize. Since FUS is well-documented to be involved in liposarcoma, lipoma and leukaemia, it is believed that when its normal housekeeping functions related to transcription are disrupted, normal cells become cancerous. Interestingly, FUS is also associated with the fatal neuron disorder amyotrophic lateral sclerosis; interruption of its normal RNA-binding functions leads to incorrect cellular localization and leads to pathologies of the neuron. Thus, FUS regulation of cellular functions is a critical component of maintenance of healthy cells.
Product Images
  • FUS Antibody (PA5-23073) in WB
    PA5-23073_WesternBlot.jpg

    Western Blot with anti-FUS Polyclonal Antibody (PA5-23073) (PA5-23073_WesternBlot.jpg)

    Western Blot with anti-FUS Polyclonal Antibody (PA5-23073)

  • FUS Antibody (PA5-23073) in WB
    PA5-23073_WesternBlot_2.jpg

    Western Blot with anti-FUS Polyclonal Antibody (PA5-23073) (PA5-23073_WesternBlot_2.jpg)

    Western Blot with anti-FUS Polyclonal Antibody (PA5-23073)

  • FUS Antibody (PA5-23073) in IF
    PA5-23073_Immunofluorescence.jpg

    Immunofluorescence with anti-FUS Polyclonal Antibody (PA5-23073) (PA5-23073_Immunofluorescence.jpg)

    Immunofluorescence with anti-FUS Polyclonal Antibody (PA5-23073)

  • FUS Antibody (PA5-23073) in IHC
    PA5-23073_Immunohistochemistry.jpg

    Immunohistochemistry with anti-FUS Polyclonal Antibody (PA5-23073) (PA5-23073_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-FUS Polyclonal Antibody (PA5-23073)

(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific