FGFR3 / CD333 Antibody (T.994.9)

FGFR3 / CD333 Monoclonal Antibody for Western blot, IF, ICC, IHC (P), IP

>> See 5 other antibodies for FGFR3 (Fibroblast Growth Factor Receptor 3, ACH, CEK2, HSFGFR3EX, JTK4, FGFR-3, fibroblast growth factor receptor 3 variant 4, hydroxyaryl-protein kinase, tyrosine kinase JTK4, FGF Receptor 3)
Synonyms:
Fibroblast Growth Factor Receptor 3, ACH, CEK2, HSFGFR3EX, JTK4, FGFR-3, fibroblast growth factor receptor 3 variant 4, hydroxyaryl-protein kinase, tyrosine kinase JTK4, FGF Receptor 3
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Monoclonal
Type: Antibody
Clone: T.994.9
Tested Species Reactivity: Human (Hu)
Immunogen: GST-FGFR-3 cytoplasmic domain fusion protein
Ordering Information
Pierce FGFR3 / CD333 Antibody (T.994.9)
Product #
MA5-14843
Size
100 ul
Price
$250.00
Purchase
Add FGFR3 / CD333 Antibody (T.994.9) to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:1000
Immunofluorescence (IF) 1:200
Immunocytochemistry (ICC) 1:200
Immunohistochemistry (Paraffin) (IHC (P)) 1:50
Immunoprecipitation (IP) 1:50
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Purification: Affinity chromatography
Storage Buffer: 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol
Preservative: <0.02% sodium azide
Storage Conditions: -20°C
Product Specific Information
It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with other related family members.
General Information
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Product Images
  • FGFR3 / CD333 Antibody (MA5-14843) in WB
    MA5-14843_WesternBlot.jpg

    Western Blot with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843) (MA5-14843_WesternBlot.jpg)

    Western Blot with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843)

    Western blot analysis of FGF Receptor 3 in recombinant human FGFR-3 cytoplasmic fragment proteins (lane 1) and extracts from KMS-11 cells (lane 2) using FGF Receptor 3 monoclonal antibody (Product # MA5-14843).
  • FGFR3 / CD333 Antibody (MA5-14843) in IF
    MA5-14843_Immunofluorescence.jpg

    Immunofluorescence with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843) (MA5-14843_Immunofluorescence.jpg)

    Immunofluorescence with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843)

    Immunofluorescent analysis of FGF Receptor 3 in KMS-11 using a FGF Receptor 3 monoclonal antibody (Product # MA5-14843) (green). DNA is labeled using a fluorescent blue dye.
  • FGFR3 / CD333 Antibody (MA5-14843) in IHC
    MA5-14843_Immunohistochemistry_2.jpg

    Immunohistochemistry with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843) (MA5-14843_Immunohistochemistry_2.jpg)

    Immunohistochemistry with anti-FGFR3 / CD333 Monoclonal Antibody [T.994.9] (MA5-14843)

    Immunohistochemical analysis of FGF Receptor 3 in paraffin-embedded small cell lung carcinoma using a FGF Receptor 3 monoclonal antibody (Product # MA5-14843).
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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