FGFR1 / CD331 Antibody

FGFR1 / CD331 Polyclonal Antibody for Western blot, IHC (P)

>> See 28 other antibodies for FGFR1 (Fibroblast Growth Factor Receptor 1, Basic fibroblast growth factor receptor 1, FGFR-1, bFGF-R, Fms-like tyrosine kinase-2, c-fgr, CD331)
Synonyms:
Fibroblast Growth Factor Receptor 1, Basic fibroblast growth factor receptor 1, FGFR-1, bFGF-R, Fms-like tyrosine kinase-2, c-fgr, CD331
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms)
Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 820 of FGFR1
Ordering Information
Pierce FGFR1 / CD331 Antibody
Product #
PA5-28564
Size
100 µL
Price
$324.00
Purchase
Tested Applications Dilution *
Western Blot (WB) 1:500-1:3000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.39mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: PBS, pH 7, with 20% glycerol
Preservative: 0.01% thimerosal
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-28564 targets FGFR1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.

The PA5-28564 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 820 of Human FGFR1.
General Information
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Product Images
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_1.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_1.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using A) 30 µg 293T whole cell lysate (B) 30 µg A431 whole cell lysate and C) 30 µg A375 whole cell lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_2.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_2.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using 30 µg SHSY5Y whole cell lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_3.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_3.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using 50µg of mouse brain lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_4.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_4.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using Various whole cell extracts (30 ?g). Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_5.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_5.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using A) 30 ?g H1299 whole cell lysate and B) 30 ?g HCT116 whole cell lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in WB
    PA5-28564_WB_6.jpg

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_WB_6.jpg)

    Western Blot with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Western blot analysis of FGFR1/CD331 using 30µg of A) HeLa and B) MOLT4 lysate. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:1000.
  • FGFR1 / CD331 Antibody (PA5-28564) in IHC (P)
    PA5-28564_IHC_1.jpg

    Immunohistochemistry (Paraffin) with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_IHC_1.jpg)

    Immunohistochemistry (Paraffin) with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Immunohistochemical analysis of FGFR1/CD331 in the cytosol of paraffin-embedded human breast carcinoma using a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:500.
  • FGFR1 / CD331 Antibody (PA5-28564) in IHC (P)
    PA5-28564_IHC_2.jpg

    Immunohistochemistry (Paraffin) with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564) (PA5-28564_IHC_2.jpg)

    Immunohistochemistry (Paraffin) with anti-FGFR1 / CD331 Polyclonal Antibody (PA5-28564)

    Immunohistochemical analysis of FGFR1/CD331 in the cytosol of paraffin-embedded human colon carcinoma using a FGFR1/CD331 polyclonal antibody (Product # PA5-28564) at a dilution of 1:500.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific