E Cadherin Antibody
E Cadherin Polyclonal Antibody for FACS, Western blot
Synonyms:
E-cadherin; Uvomorulin; Cadherin-1; CAM 120/80
Entrez Gene ID:
UniProt ID:
(Hu) P12830, (Ms) P09803
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu ) Mouse (Ms ) |
| Immunogen: | Synthetic peptide from the N-terminal region of CDH1 conjugated to KLH. |
| Ordering Information | ||||
| Pierce E Cadherin Antibody |
| Storage: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C |
| Form: | 100 µg antibody (0.25 mg/ml) in PBS with 0.09% (W/V) sodium azide. |
| Applications | Dilution * |
| Flow Cytometry (FACS) | 1:10 - 1:50 |
| Western Blot (WB) | 1:50-1:100 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA5-11548 targets E Cadherin in Western blot and flow cytometry applications and shows reactivity with Human and Mouse samples. The PA5-11548 immunogen is a synthetic peptide from the N-terminal region of CDH1 conjugated to KLH. PA5-11548 detects E Cadherin which has a predicted molecular weight of approximately 97 kDa. |
| General Information |
| This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
| Product Images |
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E Cadherin Antibody (PA5-11548) in WB
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Western Blot with anti-E Cadherin Polyclonal Antibody (PA5-11548)
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E Cadherin Antibody (PA5-11548) in WB
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Western Blot with anti-E Cadherin Polyclonal Antibody (PA5-11548)
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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E Cadherin Antibodies > E Cadherin Polyclonal Antibody PA5-11548
