Dysferlin Antibody (Ham1/7B6)

Dysferlin Monoclonal Antibody for IHC (P)

Synonyms:
dysferlin, dystrophy-associated fer-1-like 1, dystrophy-associated fer-1-like protein, fer-1-like protein 1
UniProt ID:
Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: Ham1/7B6
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Canine (Ca), Hamster (Hm), Porcine (Po), Rabbit (Rb)
Published Species Reactivity: Mouse (Ms), Rat (Rt)
Immunogen: A synthetic peptide corresponding to aa1999-2016 of human dysferlin
Ordering Information
Pierce Dysferlin Antibody (Ham1/7B6)
Product #
MA5-12568
Size
500 ul
Price
$299.00
Purchase
Add Dysferlin Antibody (Ham1/7B6) to your cart.
Tested Applications Dilution *
Immunohistochemistry (Paraffin) (IHC (P)) 1:20
Published Applications Dilution
Immunohistochemistry (IHC) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Storage Buffer: tissue culture supernatant
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
MA5-12568 targets Dysferlin in IHC (P) applications and shows reactivity with Canine, Hamster, Human, mouse, Porcine, Rabbit, and Rat samples.

The MA5-12568 immunogen is a synthetic peptide corresponding to aa1999-2016 of human dysferlin.
General Information
Dysferlin is a muscular plasma membrane protein which is defective in Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM).
Product Images
  • Dysferlin Antibody (MA5-12568) in IHC
    MA5-12568_Immunohistochemistry.jpg

    Immunohistochemistry with anti-Dysferlin Monoclonal Antibody [Ham1/7B6] (MA5-12568) (MA5-12568_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-Dysferlin Monoclonal Antibody [Ham1/7B6] (MA5-12568)

    Formalin-fixed, paraffin-embedded human skeletal muscle stained with Dysferlin antibody using peroxidase-conjugate and AEC chromogen. Note membrane staining of muscle fibers.
Publications:
Immunohistochemistry
  Species / Dilution Summary
  Ms / 0
MA5-12568 was used in immunohistochemistry to compare the localization of cardiomyocyte dysferlin in normal and dysferlin-deficient A/J mice and its effect on the development of cardiomyopathy

Am J Pathol. 2009 Dec;175(6):2299-308.
"Dysferlin deficiency and the development of cardiomyopathy in a mouse model of limb-girdle muscular dystrophy 2B."
Author(s): Chase TH, Cox GA, Burzenski L, Foreman O, Shultz LD
Number of Citations: 1
(See PubMed article )
  Rt / Not Cited
MA5-12568 was used in immunohistochemistry to study the molecular and cellular mechanisms contributing to the skeletal muscle side effects of the antibiotic daptomycin.

Muscle Nerve. 2010 Sep;42(3):385-93.
"Characterization of skeletal muscle effects associated with daptomycin in rats."
Author(s): Kostrominova TY, Hassett CA, Rader EP, Davis C, Larkin LM, Coleman S, Oleson FB, Faulkner JA
Number of Citations: 0
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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