* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
PA3-16810 reacts with Cytochrome 46 in human samples. This antibody does not react with mouse samples.
PA3-16810 has been successfully used in Western Blot, Immunohistochemistry and Immunohistochemistry-Paraffin applications.
The PA3-16810 immunogen is a synthetic peptide containing residues between 200-250 of human CYP46A1.
The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum proein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol.
Cytochrome 46 Antibody (PA3-16810) in WB PA3-16810_Westernblot4.jpg
Western Blot with anti-Cytochrome 46 Polyclonal Antibody (PA3-16810)