Part of Thermo Fisher Scientific

Complement CC9 Monoclonal Antibody (C9 53)

Complement CC9 Antibody for ELISA

Synonyms:
C9
Entrez Gene ID:
(Human) 735
UniProt ID:
P02748
Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: C9 53
Species Reactivity: Human (Hu)
Immunogen: Complement component C9.
Ordering Information
Pierce Complement CC9 Monoclonal Antibody (C9 53)
Product Number Pkg. Size Price Purchase
ABS 004-53-02 200 µg $362.00
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Storage: 4º C, store in dark
Form: 200 µg of Protein A/G purified antibody (1 mg/ml) in 0.01 M phosphate buffer, with 0.5 M NaCl and 15 mM sodium azide; pH 7.4.


Applications Dilution *
ELISA (ELISA) 1:20,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
ABS 004-53-02 is specific for complement factor C9.

ABS 004-53-02 recognizes C9 in human serum diluted 1:50 in Tris buffer (20 mM Tris-base, 1 mM MgCl2, 1 mM CaCl2 and 140 mM NaCl) and incubated for 2 hours at 37°C using a human IgM coated (10 µg/mL overnight at 4°C, blocked with PBS 7.2 + 1% BSA for 1 hour) ELISA plate.

The ABS 004-53-02 immunogen is complement factor C9.
General Information
Complement factor C9 is a 71-kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and have an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex(MAC). Primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 µg/mL, and up regulated from hepatocytes by IFN-g.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)